Microparticles of poly(hydroxybutyrate-co-hydroxyvalerate) loaded with andiroba oil: Preparation and characterization

Senhorini, Grece Aparecida; Zawadzki, Sônia Faria; Farago, Paulo Vítor; Zanin, Sandra Maria Warumby; Marques, Francisco A.

doi:10.1016/j.msec.2012.02.027

Cited by 33 publications

(16 citation statements)

References 23 publications

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“…Microcapsules containing delta-undecalactone were produced by a solvent evaporation technique using an oil-in-water emulsion [ 48 , 49 ]. We selected as shell material poly(lactic acid), a biodegradable polymer that is non-toxic, environmentally friendly and that has been thoroughly studied for its use in encapsulating hydrophobic drugs [ 50 ].…”

Section: Methodsmentioning

confidence: 99%

Field Evaluation of a Push-Pull System to Reduce Malaria Transmission

et al. 2015

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Malaria continues to place a disease burden on millions of people throughout the tropics, especially in sub-Saharan Africa. Although efforts to control mosquito populations and reduce human-vector contact, such as long-lasting insecticidal nets and indoor residual spraying, have led to significant decreases in malaria incidence, further progress is now threatened by the widespread development of physiological and behavioural insecticide-resistance as well as changes in the composition of vector populations. A mosquito-directed push-pull system based on the simultaneous use of attractive and repellent volatiles offers a complementary tool to existing vector-control methods. In this study, the combination of a trap baited with a five-compound attractant and a strip of net-fabric impregnated with micro-encapsulated repellent and placed in the eaves of houses, was tested in a malaria-endemic village in western Kenya. Using the repellent delta-undecalactone, mosquito house entry was reduced by more than 50%, while the traps caught high numbers of outdoor flying mosquitoes. Model simulations predict that, assuming area-wide coverage, the addition of such a push-pull system to existing prevention efforts will result in up to 20-fold reductions in the entomological inoculation rate. Reductions of such magnitude are also predicted when mosquitoes exhibit a high resistance against insecticides. We conclude that a push-pull system based on non-toxic volatiles provides an important addition to existing strategies for malaria prevention.

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Section: Methodsmentioning

confidence: 99%

Field Evaluation of a Push-Pull System to Reduce Malaria Transmission

et al. 2015

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“…Some pharmaceuticals have been proposed using andiroba oil, such as polymeric microparticles [ 11 ], emulsions [ 12 ], emulsions with liquid crystals [ 13 ], and even oil in water nanoemulsions [ 14 ]. Particular attention has been observed in recent years to the preparation of oil in water nanoemulsions from natural products [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

Preparation of a Nanoemulsion with Carapa guianensis Aublet (Meliaceae) Oil by a Low‐Energy/Solvent‐Free Method and Evaluation of Its Preliminary Residual Larvicidal Activity

Jesus

Almeida

Duarte

et al. 2017

Evidence-Based Complementary and Alternative Medicine

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Andiroba (Carapa guianensis) seeds are the source of an oil with a wide range of biological activities and ethnopharmacological uses. However, few studies have devoted attention to innovative formulations, including nanoemulsions. The present study aimed to obtain a colloidal system with the andiroba oil using a low-energy and organic-solvent-free method. Moreover, the preliminary residual larvicidal activity of the nanoemulsion against Aedes aegypti was evaluated. Oleic and palmitic acids were the major fatty acids, in addition to the phytosterol β-sitosterol and limonoids (tetranortriterpenoids). The required hydrophile-lipophile was around 11.0 and the optimal nanoemulsion was obtained using polysorbate 85. The particle size distribution suggested the presence of small droplets (mean diameter around 150 nm) and low polydispersity index (around 0.150). The effect of temperature on particle size distribution revealed that no major droplet size increase occurred. The preliminary residual larvicidal assay suggested that the mortality increased as a function of time. The present study allowed achievement of a potential bioactive oil in water nanoemulsion that may be a promising controlled release system. Moreover, the ecofriendly approach involved in the preparation associated with the great bioactive potential of C. guianensis makes this nanoemulsion very promising for valorization of this Amazon raw material.

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“…There are several techniques that can be used for microencapsulation of essential oils and the selection of the method is dependent on the microcapsule application, desired size, release mechanism and physicochemical properties of both the active material and the encapsulating agents. Many techniques concerning essential oil encapsulation have been reported in the literatures, such as spray drying, freeze drying, coacervation, emulsion solvent evaporation, phase separation, in situ polymerization, interfacial polymerization, modified orifice method and inclusion complexes etc.…”

Section: Introductionmentioning

confidence: 99%

Production and characterization of multinuclear microcapsules encapsulating lavender oil by complex coacervation

Xiao

Liu

Zhu

et al. 2013

Flavour & Fragrance J

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The aim of this work was to encapsulate lavender oil by complex coacervation using gelatin and gum Arabic as encapsulants. The effects of various factors including pH value, the core/wall ratio, wall material concentration, stirring speed, cross‐linkers and homogenization rate on the appearance, mean particle size, yield, loading capacity (LC) and encapsulation efficiency (EE) were investigated. The optimal conditions (pH 3.5, core/wall 3:2, wall material concentration 1%, stirring speed 450 rpm, homogenization rate 19 000 rpm and glutaraldehyde as cross‐linker) for preparing spherical multinuclear microcapsules were obtained. At the optimal conditions, the highest yield is 65.8 ± 1.0%; the maximum LC is 61.3 ± 0.7%; the highest EE is 66.0 ± 0.3%. The effect of three different cross‐linkers on the hardening effectiveness of multinuclear microcapsules containing lavender oil was investigated. Glutaraldehyde and transglutaminase exhibit similar microcapsule hardening effectiveness. When tannic acid was used instead of glutaraldehyde and transglutaminase, the mean particle size and EE remained the same as that when hardening with glutaraldehyde or transglutaminase, but the morphology obviously changes, while the yield and LC significantly decrease. Copyright © 2013 John Wiley & Sons, Ltd.

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Microparticles of poly(hydroxybutyrate-co-hydroxyvalerate) loaded with andiroba oil: Preparation and characterization

Cited by 33 publications

References 23 publications

Field Evaluation of a Push-Pull System to Reduce Malaria Transmission

Field Evaluation of a Push-Pull System to Reduce Malaria Transmission

Preparation of a Nanoemulsion with Carapa guianensis Aublet (Meliaceae) Oil by a Low‐Energy/Solvent‐Free Method and Evaluation of Its Preliminary Residual Larvicidal Activity

Production and characterization of multinuclear microcapsules encapsulating lavender oil by complex coacervation

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