Micropuncture measurements of interstitial fluid pressure in normal and inflamed dental pulp in cats

Tønder, Karin J. Heyeraas; Kvinnsland, Inger Hals

doi:10.1016/s0099-2399(83)80106-x

Cited by 79 publications

(44 citation statements)

References 13 publications

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“…The difference in pressure between inflamed and uninflamed areas can be a result of several edema-preventing mechanisms. For instance, the increase in tissue pressure might, in turn, force fluid back into lymphatics and capillaries in the nearby uninflamed tissue, consequently lowering the tissue pressure (48)(49)(50). Resilience of the ground substance of the pulp tissue might also help prevent spread of the pressure throughout the pulp (51).…”

Section: Considerations Based On Histopathologic Observations Teeth Wmentioning

confidence: 99%

Fate of the Tissue in Lateral Canals and Apical Ramifications in Response to Pathologic Conditions and Treatment Procedures

Ricucci¹,

Siqueira

2010

Journal of Endodontics

265

210

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Section: Considerations Based On Histopathologic Observations Teeth Wmentioning

confidence: 99%

Fate of the Tissue in Lateral Canals and Apical Ramifications in Response to Pathologic Conditions and Treatment Procedures

Ricucci¹,

Siqueira

2010

Journal of Endodontics

265

210

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“…51 Significant pressure differences have been observed at sites only 1 to 2mm apart. 52 Pressure from the increased tissue fluid collapses the thin-walled veins and venules only in the area of the affected pulp tissue, causing a localized vascular stasis and ischaemia, resulting in local cellular death. The gelated extracellular matrix may also act as a barrier against the spread of micro-organisms and toxic products.…”

Section: Special Features Of the Pulp With Respect To Its Circulationmentioning

confidence: 99%

An overview of the dental pulp: its functions and responses to injury

Yu¹,

Abbott²

2007

Australian Dental Journal

238

158

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The dental pulp is a unique tissue and its importance in the long-term prognosis of the tooth is often ignored by clinicians. It is unique in that it resides in a rigid chamber which provides strong mechanical support and protection from the microbial rich oral environment. If this rigid shell loses its structural integrity, the pulp is under the threat of the adverse stimuli from the mouth, such as caries, cracks, fractures and open restoration margins, all of which provide pathways for micro-organisms and their toxins to enter the pulp. The pulp initially responds to irritation by becoming inflamed and, if left untreated, this will progress to pulp necrosis and infection. The inflammation will also spread to the surrounding alveolar bone and cause periapical pathosis. The magnitude of pulp-related problems should not be underestimated since their most serious consequence is oral sepsis, which can be life threatening, and hence correct diagnosis and management are essential. Clinicians must have a thorough understanding of the physiological and pathological features of the dental pulp as well as the biological consequences of treatment interventions.

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“…In the low-compliant pulp, a nearly simultaneous increase in Pi as a result of vasodilation (Heyeraas et al, 1994) and/or venous stasis (Tonder and Kvinnsland, 1983) Consequently, capillary filtration will be reduced or absorption will occur, according to the Starling equation. This is in line with other low-compliant tissues, such as rat tail and brain, where it has been shown that vascular distension, whether caused by vasodilation or venous stasis, causes an abrupt rise in P. which counteracts a rise in net capillary filtration pressure (Wiig and Reed, 1983;Aukland and Wiig, 1984).…”

Section: Interstitial Fluid Pressurementioning

confidence: 99%

“…It was concluded that the pressure measurements did not induce any inflammatory response (Wiig, 1990 (Michelsen, 1967;Christiansen et al, 1977), kidney (Tucker and Blantz, 1978;Granger et al, 1988), and brain (Wiig and Reed, 1983 Aukland and Reed, 1993) Reported values of Pi in the dental pulp during control conditions have varied considerably, and it cannot be regarded as settled Measurements ranging from zero (Kawamura et al, 1967) and up to 60 mm Hg (Brown and Yankowitz, 1964) Fig. 2 (Tonder and Kvinnsland, 1983). The tissue pressure in the inflamed pulps was significantly increased compared with that in the contralateral controls-about 3 times higher in inflamed than in control teeth.…”

Section: Interstitial Fluid Pressure In the Pulpmentioning

confidence: 99%

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Interstitial Fluid Pressure in Normal and Inflamed Pulp

Heyeraas

Berggreen

1999

Critical Reviews in Oral Biology & Medicine

146

127

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Tissue pressure is the hydrostatic pressure in the interstitial fluid which surrounds the pulpal cells. This pressure outside the vessels is normally considerably lower than the blood pressure inside the vessels. The dental pulp has a relatively low interstitial compliance due to its enclosure between rigid dentin walls. Accordingly, even a modest increase in pulpal fluid volume will raise the tissue pressure, which may compress blood vessels, leading to ischemia and necrosis. Inflammation may lead to an increase in both interstitial fluid volume and blood volume in the low-compliant pulp and thereby increase the tissue pressure. However, the increased tissue pressure may, in turn, initiate increased lymph flow and absorption of fluid into capillaries in nearby non-inflamed tissue. Both of these latter factors will transport fluid out of the affected area and subsequently out of the tooth and consequently lower the tissue pressure. Increased tissue pressure, whether caused by increased blood volume or increased capillary filtration, will promote outward flow of fluid through exposed dentin tubules and thereby help to protect the pulp against entry of harmful substances. It seems physiologically beneficial, therefore, for the pulp to have a high tissue pressure, which promptly increases when blood flow increases due to its low compliance.

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Micropuncture measurements of interstitial fluid pressure in normal and inflamed dental pulp in cats

Cited by 79 publications

References 13 publications

Fate of the Tissue in Lateral Canals and Apical Ramifications in Response to Pathologic Conditions and Treatment Procedures

Fate of the Tissue in Lateral Canals and Apical Ramifications in Response to Pathologic Conditions and Treatment Procedures

An overview of the dental pulp: its functions and responses to injury

Interstitial Fluid Pressure in Normal and Inflamed Pulp

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