MicroRNAs Involved in Skeletal Muscle Differentiation

Luo, Wen; Nie, Qinghua; Zhang, Xiquan

doi:10.1016/j.jgg.2013.02.002

Cited by 136 publications

(125 citation statements)

References 91 publications

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“…MicroRNAs have been shown to play critical roles in skeletal muscle development and in the regulation of muscle cell proliferation and differentiation [3,4]. Wang et al [5] and Motohashi et al [6] had Identified the miRNAs which involved in bovine skeletal muscle satellite cell myogenic differentiation.…”

Section: Introductionmentioning

confidence: 99%

Identification of miR-2400 gene as a novel regulator in skeletal muscle satellite cells proliferation by targeting MYOG gene

Zhang

Tong

Sun

et al. 2015

Biochemical and Biophysical Research Communications

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Section: Introductionmentioning

confidence: 99%

Identification of miR-2400 gene as a novel regulator in skeletal muscle satellite cells proliferation by targeting MYOG gene

Zhang

Tong

Sun

et al. 2015

Biochemical and Biophysical Research Communications

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“…[23] MicroRNAs (miRNAs), which regulate the stability and/or the translational efficiency of target messenger RNAs (mRNAs), have been ascribed diverse functions, including regulation of proliferation, differentiation, senescence and death. [14] Previous studies have showed that miRNAs play critical role in skeletal muscle wasting. In chronic kidney disease (CKD) induced muscle wasting, miR-29 was suppressed in muscle, which leads to higher expression of the transcription factor Ying Yang-1, thereby suppressing myogenesis.…”

Section: Discussionmentioning

confidence: 99%

“…[12,13] MiRNAs negatively regulate gene expression by promoting degradation of target mRNAs or inhibiting their translation. [14] The role of miRNAs have been confirmed for a range of common diseases connected to impaired balance of cell proliferation, differentiation and programmed death. [15] It is reported that miRNAs have been shown to play crucial roles in muscle development and in regulation of muscle cell proliferation and…”

mentioning

confidence: 99%

Detection of the MicroRNA Expression Profile in Skeletal Muscles of Burn Trauma at the Early Stage in Rats

Chai¹

2015

Ulus Travma Acil Cerrahi Derg

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BACKGROUND: Severe burn injuries are associated with a persistent hypermetabolic response, which causes long-term loss of muscle mass that results in a clinical negative balance of nitrogen and muscle wasting. MicroRNAs (miRNAs) play a critical role in posttranscriptional regulation of gene expression, which negatively regulates gene expression by promoting degradation of target mRNAs or inhibiting their translation. However, the mechanisms of skeletal muscle wasting after severe burn involved in miRNAs still remain unclear.

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“…miRNAs have been shown to be involved in muscle cell development (Luo, Nie, & Zhang, 2013), respond to exercise both acutely and chronically (Russell et al, 2013) and be predictive of response to training (Davidsen et al, 2011).…”

Section: Epigenetic Variationmentioning

confidence: 99%

Tour de France Champions born or made: where do we take the genetics of performance?

Moran

Pitsiladis

2016

Journal of Sports Sciences

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(200 words)Cyclists in the Tour de France are endurance specialists. Twin and family studies haveshown that approximately 50% of the variance in a number of performance related phenotypes (whether measured at baseline, i.e. natural talent, or in response to training) including those important to cycling can be explained by genetic variation. Research into the specific genetic variants that are responsible has identified over 200 genes containing common genetic variants involved in the genetic predisposition to physical performance.However, typically these explain only a small portion of the variance, perhaps 1-2% and collectively they rarely explain anything approaching the 50% of the variance identified in the twin and family studies. Thus, there is a gap in our understanding of the relationship between heritability and performance. This gap may be bridged by investigation of rare variants or epigenetic variation or by altering study designs through increased collaborations to pool exiting cohorts together. Initial findings from such efforts show promising results. This mini-review will touch on the genetics and epigenetics of sporting performance, how they relate to cyclists in the Tour de France and where best future efforts may be directed as well as discuss some preliminary research findings.

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MicroRNAs Involved in Skeletal Muscle Differentiation

Cited by 136 publications

References 91 publications

Identification of miR-2400 gene as a novel regulator in skeletal muscle satellite cells proliferation by targeting MYOG gene

Identification of miR-2400 gene as a novel regulator in skeletal muscle satellite cells proliferation by targeting MYOG gene

Detection of the MicroRNA Expression Profile in Skeletal Muscles of Burn Trauma at the Early Stage in Rats

Tour de France Champions born or made: where do we take the genetics of performance?

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