The surface of a crystal made of roughly spherical molecules exposes, above its bulk rotational phase transition at T= T r , a carpet of freely rotating molecules, possibly functioning as "nanobearings" in sliding friction. We explored by extensive molecular dynamics simulations the frictional and adhesion changes experienced by a sliding C 60 flake on the surface of the prototype system C 60 fullerite. At fixed flake orientation both quantities exhibit only a modest frictional drop of order 20% across the transition. However, adhesion and friction drop by a factor of ∼ 2 as the flake breaks its perfect angular alignment with the C 60 surface lattice suggesting an entropy-driven aligned-misaligned switch during pull-off at T r . The results can be of relevance for sliding Kr islands, where very little frictional differences were observed at T r , but also to the sliding of C 60 -coated tip, where a remarkable factor ∼ 2 drop has been reported.Exploring novel routes to achieve friction control by external physical means is a fundamental goal currently pursued 1 in nanoscience and nanotechnology. The traditional lubrication control of frictional forces in macroscopic mechanical contacts is impractical at the nanoscale, where contacting surfaces are likelier to succumb to capillary forces. Novel methods for control and manipulation of friction in nano and intermediate mesoscale systems are thus constantly being explored. As an example, mechanically induced oscillations were recently shown to reduce friction and wear, an effect that has been experimentally demonstrated 2,3 . Mismatch of relative commensurability of mutually sliding lattices may prevent interlocking and stick-slip motion of the interface atoms, with a consequent friction drop (superlubricity) 4 . The application of external fields (electric, magnetic, etc.) to the sliding contact was also exploited to tune effectively the frictional response in different kind of tribological systems 5-8 . Another, subtler route worth exploring is the possible change of adhesion and friction experienced by a nanoslider when a collective property of the substrate, for example some pre-existing ordering is altered under the action of an external field, or of temperature. In a given state of the substrate, its order parameter magnitude, polarization, critical fluctuations, etc., determines in a unique manner the friction, affecting both the efficiency of * andrea. the slider-substrate mechanical coupling, and the rate of generation and transport of the frictional Joule heat away from the sliding contact. A toy-model study 9 showed that the variation of stick-slip friction, caused by a structural order parameter switching between order and disorder, can indeed be large and observable. Hard to predict on general terms, the frictional variation occurring in a real case will depend on the system, the mechanism, the material. In this work we study the friction experienced by a nanosized island or tip-attached flake sliding over the surface of a molecular crystal made up o...