Microscale patterned surfaces reduce bacterial fouling-microscopic and theoretical analysis

Vasudevan, Ravikumar; Kennedy, Alan J.; Merritt, Megan; Crocker, Fiona H.; Baney, Ronald H.

doi:10.1016/j.colsurfb.2014.02.037

Cited by 101 publications

(80 citation statements)

References 37 publications

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“…While in the case of drug delivery systems the release of antimicrobial compounds is mainly relevant up to 24 h (retard release), for antibiotic-eluting coatings, the finite release property (i.e., after a certain time point they will release below minimal inhibitory concentration of the antibiotic) limits their use in implants. [47] For instance, nanoengineered topography can highly reduce bacteria attachment by decreasing the area of contact between surface and microbes, [48] and the attachment of blood cells to surfaces can be reduced by coating them with tethered perfluorocarbon chains to avoid thrombosis. [46] However, for long-term implants, continuous strong release of antibiotics is crucial within the first few hours postimplantation, while the immune system is weakened and the implant is most susceptible to bacterial colonization.…”

Section: Antimicrobial Durabilitymentioning

confidence: 99%

“…Adapted with permission. [48] Capture and killing of bacteria has been achieved by functionalization of silicon nanopillars with bacteria-binding molecules [79] and functionalization with poly mer brushes entrapping an antibacterial enzyme, lysozyme. decoration with silver or copper nanoparticles [77] or quaternized polymer brushes.…”

Section: Synthetic Micro-and Nanostructured Surfacesmentioning

confidence: 99%

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Nanoscience‐Based Strategies to Engineer Antimicrobial Surfaces

et al. 2018

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Microbial contamination and biofilm formation of medical devices is a major issue associated with medical complications and increased costs. Consequently, there is a growing need for novel strategies and exploitation of nanoscience‐based technologies to reduce the interaction of bacteria and microbes with synthetic surfaces. This article focuses on surfaces that are nanostructured, have functional coatings, and generate or release antimicrobial compounds, including “smart surfaces” producing antibiotics on demand. Key requirements for successful antimicrobial surfaces including biocompatibility, mechanical stability, durability, and efficiency are discussed and illustrated with examples of the recent literature. Various nanoscience‐based technologies are described along with new concepts, their advantages, and remaining open questions. Although at an early stage of research, nanoscience‐based strategies for creating antimicrobial surfaces have the advantage of acting at the molecular level, potentially making them more efficient under specific conditions. Moreover, the interface can be fine tuned and specific interactions that depend on the location of the device can be addressed. Finally, remaining important challenges are identified: improvement of the efficacy for long‐term use, extension of the application range to a large spectrum of bacteria, standardized evaluation assays, and combination of passive and active approaches in a single surface to produce multifunctional surfaces.

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Section: Antimicrobial Durabilitymentioning

confidence: 99%

Section: Synthetic Micro-and Nanostructured Surfacesmentioning

confidence: 99%

Nanoscience‐Based Strategies to Engineer Antimicrobial Surfaces

et al. 2018

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“…Recently, topographic approaches for controlling biological response have become increasingly common . Numerous studies have demonstrated that micro‐ or nanostructured surfaces influence cell behaviors, reduce platelet adhesion/activation, and inhibit bacterial adhesion/biofilm formation . Among them, the ability to inhibit bacterial adhesion through topographic approach might be more attractive since the topographic approach does not require incorporating antibiotic agents into materials that might lead to antibiotic resistance of bacteria.…”

Section: Introductionmentioning

confidence: 99%

“…6,15 Numerous studies have demonstrated that micro-or nanostructured surfaces influence cell behaviors, 21,22 reduce platelet adhesion/activation, 23,24 and inhibit bacterial adhesion/ biofilm formation. [25][26][27][28][29] Among them, the ability to inhibit bacterial adhesion through topographic approach might be more attractive since the topographic approach does not require incorporating antibiotic agents into materials that might lead to antibiotic resistance of bacteria. This provides a concept and design strategy for designing a new generation of implanted medical devices with truly biocompatible materials.…”

Section: Introductionmentioning

confidence: 99%

Protein adsorption, platelet adhesion, and bacterial adhesion to polyethylene-glycol-textured polyurethane biomaterial surfaces

Siedlecki

2015

J. Biomed. Mater. Res.

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Traditional strategies for surface modification to enhance the biocompatibility of biomaterials often focus on a single route utilizing either chemical or physical approaches. This study combines the chemical and physical treatments as applied to poly(urethane urea) (PUU) biomaterials to enhance biocompatibility at the interface for inhibiting platelet-related thrombosis or bacterial adhesion-induced microbial infections. PUU films were first textured with submicron patterns by a soft lithography two-stage replication process, and then were grafted with polyethylene glycol (PEG). A series of biological response experiments including protein adsorption, platelet adhesion/activation, and bacterial adhesion/biofilm formation showed that PEG-grafted submicron textured biomaterial surfaces were resistant to protein adsorption, and greatly increased the efficiency in reducing both platelet adhesion/activation and bacterial adhesion/biofilm formation due to the additive effects of physical topography and grafted PEG. Results suggest that a combination of chemical modification and surface texturing will be more efficient in preventing biomaterial-associated thrombosis and infection of biomaterials. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 668-678, 2017.

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“…It was concluded that offering an increased contact area to the cells resulted in more efficient electron transfer, which was consistent with the direct electron transfer pathway achieved by S. putrefaciens (Kim et al, 1999) (see Section 4.3). However, it may be noted that micro-holes of side 4-5 µm can increase the contact area for individual bacteria but they may be less favourable for biofilm development than micro-pillar structures because they isolate cells or colonies from each other (Vasudevan et al, 2014;Yang et al, 2015). (Table 4) At the nano-scale, it is difficult to make a strict distinction between random nano-roughness, which is generally obtained by global surface treatments, and nano-structuring, which should result in well-patterned surfaces.…”

Section: Surface Micro-structuringmentioning

confidence: 99%

Impact of electrode micro- and nano-scale topography on the formation and performance of microbial electrodes

Champigneux

Délia

Bergel

2018

Biosensors and Bioelectronics

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From a fundamental standpoint, microbial electrochemistry is unravelling a thrilling link between life and materials. Technically, it may be the source of a large number of new processes such as microbial fuel cells for powering remote sensors, autonomous sensors, microbial electrolysers and equipment for effluent treatment. Microbial electron transfers are also involved in many natural processes such as biocorrosion. In these contexts, a huge number of studies have dealt with the impact of electrode materials, coatings and surface functionalizations but very few have focused on the effect of the surface topography, although it has often been pointed out as a key parameter impacting the performance of electroactive biofilms. The first part of the review gives an overview of the influence of electrode topography on abiotic electrochemical reactions. The second part recalls some basics of the effect of surface topography on bacterial adhesion and biofilm formation, in a broad domain reaching beyond the context of electroactivity. On these well-established bases, the effect of surface topography is reviewed and analysed in the field of electroactive biofilms. General trends are extracted and fundamental questions are pointed out, which should be addressed to boost future research endeavours. The objective is to provide basic guidelines useful to the widest possible range of research communities so that they can exploit surface topography as a powerful lever to improve, or to mitigate in the case of biocorrosion for instance, the performance of electrode/biofilm interfaces.

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Microscale patterned surfaces reduce bacterial fouling-microscopic and theoretical analysis

Cited by 101 publications

References 37 publications

Nanoscience‐Based Strategies to Engineer Antimicrobial Surfaces

Nanoscience‐Based Strategies to Engineer Antimicrobial Surfaces

Protein adsorption, platelet adhesion, and bacterial adhesion to polyethylene-glycol-textured polyurethane biomaterial surfaces

Impact of electrode micro- and nano-scale topography on the formation and performance of microbial electrodes

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