Microstructural Analysis of Porous Composite Materials: Dynamic Imaging of Drug Dissolution and Diffusion Through Porous Matrices

Monitoring lidocaine single‐crystal dissolution by ultraviolet imaging

“…Alternatively, for example, in the case of unexpected dissolution behaviour, more detailed information might be gained by monitoring the dissolution process immediately next to the surface of a small amount of the dissolving material. Imaging techniques capable of providing spectrally, spatially and temporally resolved information are emerging tools in more detailed studies of drug dissolution due to their potentially high information content 9–15. Ultraviolet (UV) imaging technology, which has recently become commercially available, may constitute an alternative and complementary technology to, for instance, Fourier transform infrared and magnetic resonance imaging.…”

Real-Time UV Imaging of Nicotine Release from Transdermal Patch

“…Thus, there is a need for information-rich in vitro characterization methods to meet the increasing demands for efficient formulation development within the pharmaceutical industry. Imaging techniques providing spectrally, spatially, and temporally resolved information have shown to be particularly useful in this context (6)(7)(8)(9)(10)(11)(12).…”

Modeling of the Dissolution Kinetics of Arbutus Wild Berries-Based Tablets as Evaluated by Electric Conductivity

“…In fact, while the common standard dissolution testing like described by United States Pharmacopoeia is generally used to investigate solid delivery systems, some authors have nevertheless adapted a specific methodology. Thus, taking into account the limitation of performing the USP dissolution test in relation to their specific conditions, Young et al (2008) have assembled a large reservoir upon a magnetic stirrer to simulate the pharmacopoeia dissolution test. The electrical conductivity was measured by means of conductivity meter (Type EC 214 HANNA).…”