Metals are often used in a wide range of biomedical applications since they have good mechanical characteristics, like higher strength, ductility, and toughness. However, the primary disadvantage of metallic biomaterials is their rapid reactivity, which causes corrosion when exposed to physiological conditions like body fluids. When exposed to body fluids, the metallic biomaterial is subjected to wear and corrosion; hence, the mechanical properties are reduced. Corrosion resistance, which also has a significant impact on biocompatibility, affects the efficacy and longevity of an implant material. In this chapter, the body environment will be carefully examined and the potential impacts of corrosion on the biocompatibility of various biomaterials will be highlighted. The fundamentals of implant failure, recovery, and failure mechanisms will be mentioned, and the most common in-vitro and in-vivo corrosion processes will be discussed. Finally, the different methods for preventing biomaterial corrosion will be emphasised.