Microstructure, mechanical, corrosion properties and cytotoxicity of beta‑calcium polyphosphate reinforced ZK61 magnesium alloy composite by spark plasma sintering

Cui, Zeqin; Zhang, Yakai; Cheng, Yinlong; Gong, Dianqing; Wang, Wenxian

doi:10.1016/j.msec.2019.02.050

Cited by 50 publications

(24 citation statements)

References 40 publications

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“…HA (Ca 10 (PO 4 ) 6 (OH) 2 ) is another calcium phosphate–based bioceramic material which has been extensively used as a reinforcing material in Fe- [ 300 ], Mg- [ 301 , 302 ], and Zn-based biodegradable matrices [ 91 , 303 ]. HA possesses a hexagonal crystal structure with a characteristic Ca/P ratio of 1.67. β-TCP has similar compositional properties to human bone and is extensively used for orthopedic applications due to its excellent biocompatibility with bone cells and its potential to stimulate new bone ingrowth [ 304 ]. Therefore, the addition of β-TCP particles as reinforcements in biodegradable metal matrices not only enhances their mechanical properties, but also significantly increases the biocompatibility of these composite materials [ 293 ].…”

Section: Zn-based Compositesmentioning

confidence: 99%

Recent research and progress of biodegradable zinc alloys and composites for biomedical applications: Biomechanical and biocorrosion perspectives

Kabir

Munir

Wen

et al. 2021

Bioactive Materials

235

143

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Biodegradable metals (BMs) gradually degrade in vivo by releasing corrosion products once exposed to the physiological environment in the body. Complete dissolution of biodegradable implants assists tissue healing, with no implant residues in the surrounding tissues. In recent years, three classes of BMs have been extensively investigated, including magnesium (Mg)-based, iron (Fe)-based, and zinc (Zn)-based BMs. Among these three BMs, Mg-based materials have undergone the most clinical trials. However, Mg-based BMs generally exhibit faster degradation rates, which may not match the healing periods for bone tissue, whereas Fe-based BMs exhibit slower and less complete in vivo degradation. Zn-based BMs are now considered a new class of BMs due to their intermediate degradation rates, which fall between those of Mg-based BMs and Fe-based BMs, thus requiring extensive research to validate their suitability for biomedical applications. In the present study, recent research and development on Zn-based BMs are reviewed in conjunction with discussion of their advantages and limitations in relation to existing BMs. The underlying roles of alloy composition, microstructure, and processing technique on the mechanical and corrosion properties of Zn-based BMs are also discussed.

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Section: Zn-based Compositesmentioning

confidence: 99%

Recent research and progress of biodegradable zinc alloys and composites for biomedical applications: Biomechanical and biocorrosion perspectives

Kabir

Munir

Wen

et al. 2021

Bioactive Materials

235

143

View full text Add to dashboard Cite

show abstract

“…Mg/β-TCP composites prepared by powder metallurgy route for biomedical applications have been studied by several authors. , In a recent study, Mg/β-TCP composites containing 10 and 20 vol % β-TCP were fabricated through spark plasma sintering . Microstructures of Mg/β-TCP composites showed unreacted β-TCP and MgO as a second phase in its matrix (Figure a–d).…”

Section: Processing Of Mg Ceramic Reinforced Compositesmentioning

confidence: 99%

Recent Developments in Magnesium Metal–Matrix Composites for Biomedical Applications: A Review

Dutta

Gupta

Roy

2020

ACS Biomater. Sci. Eng.

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Recently, there is a growing interest in developing magnesium (Mg) based degradable biomaterial. Although corrosion is a concern for Mg, other physical properties, such as low density and Young’s modulus, combined with good biocompatibility, lead to significant research and development in this area. To address the issues of corrosion and low yield strength of pure Mg, several approaches have been adopted, such as, composite preparation with suitable bioactive reinforcements, alloying, or surface modifications. This review specifically focuses on recent developments in Mg-based metal matrix composites (MMCs) for biomedical applications. Much effort has gone into finding suitable bioactive, bioresorbable reinforcements and processing techniques that can improve upon existing materials. In summary, this review provides a comprehensive overview of existing Mg-based composite preparation and their mechanical and corrosion properties and biological responses and future perspectives on the development of Mg-based composite biomaterials.

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“…Finally, the green compact is removed from the punch and is kept inside a closed chamber muffle furnace for sintering. The sintering temperature is always below the melting point of ceramic powders [15]. After heating, the composite specimens are taken out and cooled in open air [16].…”

Section: Fabrication Methodsmentioning

confidence: 99%

Process Modelling and Experimental Analysis of Optimal Specimen Selection in Organic CMCs

Rajesh¹,

Kalita²,

Gao³

2022

Computers, Materials &Amp; Continua

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Bone grafting is a surgical restructuring procedure of replacing broken bones and reconstructing missing bone pieces so that complex bone fractures can be repaired to avoid any serious health risk as well as permanent bone disfiguration. Normally, human bones tend to regenerate and heal completely from fracture. But it needs a small scaffold to provide the necessary space to grow. Bone implants allow a broken bone to grow seamlessly. Traditionally, non-corrosive metal alloys are used for fixing broken bones. A metal plate is fastened between two ends of broken bones to join them. However, issues like high weight, high cost, low wear resistance, etc. led to the emergence of ceramics and ceramic-based composites in surgical engineering. Recent trends indicate the usage of organic ceramics and their associated composites as biomimetic materials for prostheses and other biomedical applications. This research paper deals with the fabrication of one such type of ceramic matrix composite (CMC) specimen with sea sponge and cuttlebone using powder metallurgy process by varying composition of cuttlebone, the particle size of the ceramics and sintering temperature of green compacts. Evaluation of thermo-mechanical properties and optimization of process parameters is carried out using the preferential selection index (PSI) method. The results obtained from this technique are further validated using Multi-Level General Factorial Design (MLGFD).

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Microstructure, mechanical, corrosion properties and cytotoxicity of beta‑calcium polyphosphate reinforced ZK61 magnesium alloy composite by spark plasma sintering

Cited by 50 publications

References 40 publications

Recent research and progress of biodegradable zinc alloys and composites for biomedical applications: Biomechanical and biocorrosion perspectives

Recent research and progress of biodegradable zinc alloys and composites for biomedical applications: Biomechanical and biocorrosion perspectives

Recent Developments in Magnesium Metal–Matrix Composites for Biomedical Applications: A Review

Process Modelling and Experimental Analysis of Optimal Specimen Selection in Organic CMCs

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