a b s t r a c tA micro-mechanical modelling methodology is presented for predicting fretting fatigue crack nucleation in Ti-6Al-4V. The methodology is based on a combination of (i) a unit cell crystal plasticity model of Ti6Al-4V, (ii) a frictional contact model of an experimental fretting wear configuration, and (iii) implementation of a microstructure-sensitive fatigue indication parameter for prediction of crack nucleation. A novel micro-mechanical method for wear prediction is presented. A key finding is the important role of cyclic micro-plasticity in ostensibly elastic loading regimes in fretting wear, resulting in significant effects on distributions of salient fretting contact variables such as contact pressure.