Microwave-assisted extraction of scutellarin from Erigeron breviscapus Hand-Mazz and its determination by high-performance liquid chromatography

Gao, Min; Huang, Wei; RoyChowdhury, Moytri; Liu, Chun-Zhao

doi:10.1016/j.aca.2007.04.004

Cited by 51 publications

(27 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Anthocyanin from roselle has been previously extracted using various solvents such as water [63][64][65][66][67][68], methanol [63], ethanol acidified by HCl [69] and in the instant pressure drop system solvent [70]. A high solvent ratio with microwave-assisted extraction showed consistent results [71,72]. When large quantities of solvent were utilized, the extraction yield initially increased and then decreased as the solid-to-liquid ratio decreased [72,73].…”

Section: Effect Of Ratio Of Liquid To Solid (Water: Hibiscus Sabdarifmentioning

confidence: 99%

“…When large quantities of solvent were utilized, the extraction yield initially increased and then decreased as the solid-to-liquid ratio decreased [72,73]. When the amount of solvent was reduced (high-solid herbal materials), microwave energy may have been absorbed and dispersed by the large amount of plant materials [71], thereby increasing the solid mass, and decreasing the surface area available for solvent to penetrate the plant materials and solubilize the target molecules [74].…”

Section: Effect Of Ratio Of Liquid To Solid (Water: Hibiscus Sabdarifmentioning

confidence: 99%

See 1 more Smart Citation

Mircowave-Assisted Extraction of Phytochemical Constituents in Roselle (Hibiscus sabdariffa L.)

Nguyen

2020

JPRI

View full text Add to dashboard Cite

Roselle (Hibiscus sabdariffa L.) is natural source of valuable components such as phenolics, flavonoids and anthocyanins. Anthocyanin is normally used in the food technology to replace synthetic pigments as well as medicinal properties due to antioxidants. Microwave irradiation is a feasible green solvent extraction method receiving great attention as it utilizes solvent at elevated temperature and controlled pressure conditions. Microwave extraction emerges as a promising inexpensive, simple and efficient technique. In our research, various variable like microwave power (20, 40, 60, 80, 100 W), microwave frequency (10, 20, 30, 40, 50 GHz), the microwave irradiation duration (5, 10, 15, 20, 25 min), liquid to solid ratio (water: material, 2:1, 3:1, 4:1, 5:1, 6:1), extraction temperature (50, 55, 60, 65, 70°C), number of extraction cycles (1, 2, 3, 4, 5) influencing to the microwave-assisted extraction of phytochemicals in roselle (Hibiscus sabdariffa L.) calyx were thoroughly examined. Total total phenolic (mg GAE/ 100 g), total flavonoid (mg GE/ 100 g), anthocyanin (mg/100 g) were key indicators to define the optimal variable. Our results revealed that microwave power at 80 W, frequency 40 GHz, duration 15 min, liquid to solid ratio 4:1, temperature 55°C, 4 cycles of extraction were appropriate for extraction of phytochemical components inside roselle (Hibiscus sabdariffa L.) calyx.

show abstract

Section: Effect Of Ratio Of Liquid To Solid (Water: Hibiscus Sabdarifmentioning

confidence: 99%

Section: Effect Of Ratio Of Liquid To Solid (Water: Hibiscus Sabdarifmentioning

confidence: 99%

Mircowave-Assisted Extraction of Phytochemical Constituents in Roselle (Hibiscus sabdariffa L.)

Nguyen

2020

JPRI

View full text Add to dashboard Cite

show abstract

“…The HPLC analysis was carried out on an Agilent 1100 system which is composed of a quaternary pump with a degasser, a thermostatted column compartment, a variable wavelength detector, an auto-sampler with a 20 l injection loop and 1100 ChemStation software [13]. Sample analyses were performed on a Shimadzu C 18 column (250 mm × 4.6 mm i.d., 5 m) with a liner elution using 0.1% TFA:methanol (60:40) in 20 min.…”

Section: Hplc Analysis Of Scutellarinmentioning

confidence: 99%

Separation of scutellarin from crude extracts of Erigeron breviscapus (vant.) Hand. Mazz. by macroporous resins

Gao

Huang

Liu

2007

Journal of Chromatography B

Self Cite

View full text Add to dashboard Cite

“…The active components of DZXX injection are caffeic acid ester fraction (Caf) and scutellarin (Scu). [ 13 , 16 – 19 ] Recent pharmacological and animal experiments prove that Scu can reduce apoptosis and oxidative stress. [ 20 ] Besides, Caf and Scu have potential therapeutic neuroprotection for cerebral infarction through astrocytes , [ 21 ] including regulating nitric oxide production, [ 22 ] inhibiting hypoxia induced cytotoxicity, [ 21 , 23 ] and rescuing neuronal damage.…”

Section: Introductionmentioning

confidence: 99%

Dengzhanxixin injection for cerebral infarction

et al. 2017

View full text Add to dashboard Cite

Background:No systematic review has been published in English of Dengzhanxixin (DZXX) injection for cerebral infarction. The aim of this systematic review was to assess the effects and safety of DZXX injection for cerebral infarction.Methods:Eight databases were searched from their inception. Randomized controlled trials (RCTs) related to DZXX for cerebral infarction in English or Chinese without restrictions on the publication status were included. Neurological deficit, quality of life, and response rates were analyzed. Adverse events were also investigated.Results:Twenty-three randomized controlled trials (RCTs) with 2291 participants were included. Meta-analysis showed that DZXX injection plus routine western therapy was better than routine western therapy alone for reducing neurologic deficit (MD –2.86, 95% CI –3.87 to –1.86), for improving quality of life (MD 9.48, 95% CI 8.34–10.63), and for improving response rates (RR 1.20, 95% CI 1.15–1.25). No serious adverse drug events (ADE) were reported.Conclusions:DZXX injection may have a potential therapeutic effect for cerebral infarction in reducing neurologic deficit, improving life quality and response rates. However, we could not draw any definitive conclusions due to the insufficient evidences. More high-quality trials are needed to provide more strong evidence and to assess the safety of DZXX injection.

show abstract

Microwave-assisted extraction of scutellarin from Erigeron breviscapus Hand-Mazz and its determination by high-performance liquid chromatography

Cited by 51 publications

References 16 publications

Mircowave-Assisted Extraction of Phytochemical Constituents in Roselle (Hibiscus sabdariffa L.)

Mircowave-Assisted Extraction of Phytochemical Constituents in Roselle (Hibiscus sabdariffa L.)

Separation of scutellarin from crude extracts of Erigeron breviscapus (vant.) Hand. Mazz. by macroporous resins

Dengzhanxixin injection for cerebral infarction

Contact Info

Product

Resources

About