Microwave-assisted facile synthesis of poly(luminol-co-phenylenediamine) copolymers and their potential application in biomedical imaging

Abstract

Development of bioimaging agents based on poly(o-phenylendiamine and luminol).

Development of a near infrared novel bioimaging agent via co-oligomerization of Congo red with aniline and o-phenylenediamine: experimental and theoretical studies

“…6(c), revealed intense peaks at 550 nm, 670 nm, 760 nm and 850 nm in neutral and basic media while the peaks in acidic medium were observed around 520 nm, 710 nm and 805 nm respectively. It has been reported in literature that the emission spectrum of pure POPD exhibits peaks around 550 nm 3,33 but in this case the peaks related to the POPD content in the cooligomer were noticed at higher emission wavelengths due to co-oligomerization.…”

“…The molar ratios of the cooligomer composition were calculated by comparing the integrated areas of -NH protons as reported in our previous studies. 3,32 The integrated areas of NH protons were calculated to be 24 : 76 (PCR : PANI) for PCR-co-PANI while it was observed to be 42 : 58 (PCR : POPD) for PCR-co-POPD. The co-oligomer composition was observed to be almost equal to the feed molar ratio in case of PCR-co-POPD while it was noticed to be different than the feed ratio for PCR-co-PANI.…”

“…The % viability was calculated using formula reported in previous studies. 3,4 % viability ¼ mean OD of treated cells mean OD of untreated cells ðcontrolÞ Â 100…”

“…3, showed sharp peaks at 2q ¼ 27.25 , 32.18 , 37.84 , 44.91 and 45.33 corresponding to (101), (111), (117), (124) and (134) planes respectively. 3,32,33 The XRD pattern of PCR-co-PANI revealed a pronounced high angle peak at 2q ¼ 31.7 indicating amorphous structure of the cooligomer. The XRD prole of PCR-co-POPD exhibited three intense peaks at 2q ¼ 19.58 , 27.53 and 31.56 indicating a semi-crystalline morphology.…”

Luminol‐Pendant Chemiluminescent Polymethacrylamide‐Based Polymers for Peroxide Sensing in Live Cell Imaging.

“…Luminol was also electrocopolymerized with other monomers like, pyrrole, aniline, thiophene, acetylene and indole, 3,3’,5,5’‐tetramethylbenzidine and biotinylated pyrroles [17](a) which provided more interesting ways of altering the properties of polymeric matrix materials. Microwave assisted copolymerization of Luminol with o ‐phenylenediamine was also recently reported …”