Microwave-Assisted Solvent Free Synthesis of Spiro-Indole Derivative

Abstract

Abstract

Microwave-Induced Synthesis of Some Novel Fungicidal Pyrazole Derivatives

“…Heterocyclic compounds have been reported to be synthesized by various conventional methods [4][5][6] which consume higher amount of reactants, solvents, catalysts, hazardous chemicals and tediously longer reaction time. Nowadays variety of heterocyclic compounds have been synthesized under microwave irradiations by using inorganic solid supports [7][8][9][10] like acidic, basic and neutral alumina or montmorilonite K 10 clay based on the reaction conditions.…”

Alumina Supported Synthesis of Some α,β– Unsaturated Heterocyclic Acids

“…by using alums 18 as catalyst which is a cheap and household material. This ongoing interest in alum catalyst has got recent application in Doebner reaction 19,20 for the synthesis of several homocyclic 21 and heterocyclic 22,23 unsaturated acids or acrylic acids. These recent trends in organic synthesis prompted the author to synthesize novel heterocyclic α, βunsaturated acids under the solid support of alumina by adopting microwave irradiations in solvent freecondition.…”

A New Route for the Synthesis of Quinazolinones

“…Quinazolinones are important heterocycles with wider range of microbial activities such as anti-malarial, anti-cancer, anti-inflammatory, anti-hypertensive, anti-convulsant, anti-HIV, etc (Tereshina et al1995).These compounds have been synthesized from various precursors by adopting different methods (Zulykama et al 2004. Most of the methods are conventional and hazardous from the environmental point of view (Mishra 2009). They take longer time for completion with low yield and involve higher amount of acids, bases and other related chemicals , Caddick 1995.…”