Microwave-assisted synthesis of tetrasubstituted aryl imidazole based polymers via cascade polycondensation process

Imine-based multicomponent polymerization: Concepts, structural diversity and applications

“…So far, there is only one report on the Radziszewski type II polymerization in the literature. [180] In this work, a series of tetrasubstituted poly(aryl imidazole)s was produced from various bis(aryl 1,2-diketone)s, bis(aryl aldehyde)s, mono-aryl amines and ammonium acetate (Fig. 25).…”

The multicomponent Debus–Radziszewski reaction in macromolecular chemistry

“…Based on a similar process, the same research group has investigated the synthesis of tetrasubstituted poly(arylimidazole)s (Fig. 13B) 67 . Different polymers with high molecular weight were obtained and display very good thermal stabilities (357 °C < Td5% < 513 °C).…”

Microwave-Assisted Synthesis of Bioactive Six-Membered Heterocycles and Their Fused Analogues

“…Thus, in the presence of a catalytic amount of Yb(OTf)3 and under MW irradiation with silica gel, several series of 2-amino-3- On the other hand, El-Borai et al [31] described a new synthesis of pyrazolo [3,4-b]pyridine derivatives through a one-pot multi-component reaction. In this synthesis, 5-amino-1-phenyl-3-(pyridin-3-yl)-1H-pyrazole (11) was allowed to react with either 4-anisaldehyde (12) and p-substituted α-keto-nitriles 13 or with pyruvic acid (16) and some aromatic aldehydes 15 in acetic acid (Scheme 2). The reaction was carried out by conventional heating and under MW irradiation.…”

“…Three, four and five-membered ring systems have been previously reviewed by our group and are not addressed in this issue [17]; the synthesis of seven-membered ring and macrocyclic systems will be reviewed by us shortly. essential oil extraction and biochemical processes [10][11][12][13][14]. In addition, the MW-assisted organic syntheses can also lead in short time to large libraries of small-sized heterocyclic compounds featuring high molecular diversity with potential bioactivities [15,16].…”