Middle East Respiratory Syndrome Coronavirus (MERS CoV): An Emerging Pathogen

Ahasan, H A M Nazmul; Das, Aparna; Chowdhury, Mostofa Kamal; Minnat, Baharul

doi:10.3329/jom.v14i2.19634

Cited by 5 publications

(7 citation statements)

References 22 publications

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“…The spike proteins play a crucial role in binding to the host’s cellular receptor which has been identified as Dipeptidyl peptidase 4(DDP4) [23] , [24] . The DDP4 receptors are relatively more abundant in the lower airways compared to the upper airways with greater expression in the non-ciliated bronchial epithelial cells as well as Type 1 and 2 pneumocytes and MERS-CoV, unlike SARS-CoV, does not target the ACE2-expressing ciliated epithelial cells [19] .…”

Section: Pathogenesismentioning

confidence: 99%

“…MERS-CoV remains a high priority pathogen for the global health community because of its pandemic potential and the significant case fatality rate of 34.3% [17] . MERS-CoV continues to cause intermittent sporadic cases in the Middle East as well as nosocomial outbreaks, thus underpinning the substantial risk of widespread global spread with the current ease of global travel [18] , [19] . Evidence now exists that Dromedary camels are the host reservoir species for MERS-CoV and that transmission from these camels to humans has been documented [20] ..…”

Section: Epidemiologymentioning

confidence: 99%

“…Approximately 25% of cases of MERS-CoV were attributable to either direct or indirect contact with the host reservoir (Dromedary camels) whilst about 50% of cases were linked to nosocomial (healthcare associated) outbreaks involving healthcare workers, patients and visitors to facilities with positive cases [21] , [22] .More severe cases were seen in older males with underlying medical conditions, especially diabetes, chronic respiratory and kidney diseases [19] .…”

Section: Epidemiologymentioning

confidence: 99%

“…The incubation period ranges from 2-14 days with a mean of 5.2 days (95%CI 1.9-14.7) in hospital-associated clusters [27] . The leading presenting symptoms of MERS-CoV are fever, cough, shortness of breath, myalgia, diarrhoea and vomiting [19] , [21] . Majority of the diagnosed cases were symptomatic, with fewer asymptomatic cases are identified through contact tracing of exposed individuals [26] .…”

Section: Clinical Course and Outcome In Pregnancymentioning

confidence: 99%

See 3 more Smart Citations

Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-1) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections in pregnancy – An overview

Babarinsa

Okunoye

Odukoya

2021

European Journal of Obstetrics & Gynecology and Reproductiv

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Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-1) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections, like most other viruses that affect the respiratory tract can cause severe maternal illness and adverse pregnancy outcomes. They are not only highly transmissible (acquired through droplets), but Host reservoirs such as dromedary camels for MERS-CoV and masked palm civet for SARS-CoV are critical links in the onset of outbreaks. Clinically they present with flu-like symptoms and therefore a high index of suspicion is required to ensure timely diagnosis and tailored management. Although there are not many reported series on these infections in pregnancy they seem to be associated with an increased risk of preterm delivery and maternal mortality. Diagnosis is made by PCR from nasopharyngeal swabs. There are currently no effective anti-viral agents for these viruses but following infections various agents have been administered to patients. The most important aspect of management should be early identification of deterioration and intensive support and prevention of transmission. Our understanding of the evidence of the impact of both infections on pregnancies suggests the potential for future repeat outbreaks, hence the importance of maintaining vigilance across healthcare systems.

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Section: Pathogenesismentioning

confidence: 99%

Section: Epidemiologymentioning

confidence: 99%

Section: Epidemiologymentioning

confidence: 99%

Section: Clinical Course and Outcome In Pregnancymentioning

confidence: 99%

See 2 more Smart Citations

Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-1) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections in pregnancy – An overview

Babarinsa

Okunoye

Odukoya

2021

European Journal of Obstetrics & Gynecology and Reproductiv

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“…It causes fever, coughing and a shortness of breath that can turn into pneumonia. The MERS virus is characterized by a much higher (up to 50%) mortality rate ( Ahasan et al, 2013 ). Coronavirus disease 2019 (COVID-19) belongs to the group of viruses that infect many species of animals, including humans.…”

Section: Introductionmentioning

confidence: 99%

Numerical analysis of factors, pace and intensity of the corona virus (COVID-19) epidemic in Poland

Kowalski

Szwagrzyk

Kiełpińska

et al. 2021

Ecological Informatics

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This article focuses on a statistical analysis of the corona virus disease 2019 (COVID-19) data that appeared until November 31, 2020 in Poland. The studied database, expressed in terms of both population and air pollution (particulate) indicators, is provided mainly by the Airly company, the Central Statistical Office (GUS) and the Rogalski project. The particular measured factors, which underwent standardization, were assessed for mutual dependency by means of a Pearson correlation coefficient and analysed by a linear regression. Based on the presented models, our results indicate that air quality (air pollution level) is the most important factor in the context of enabling COVID-19 case load increase in Poland.

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Medical Image Classification for Coronavirus Disease (COVID-19) Using Convolutional Neural Networks

Al-Zubaidi

Mijwil

2021

eijs

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The coronavirus is a family of viruses that cause different dangerous diseases that lead to death. Two types of this virus have been previously found: SARS-CoV, which causes a severe respiratory syndrome, and MERS-CoV, which causes a respiratory syndrome in the Middle East. The latest coronavirus, originated in the Chinese city of Wuhan, is known as the COVID-19 pandemic. It is a new kind of coronavirus that can harm people and was first discovered in Dec. 2019. According to the statistics of the World Health Organization (WHO), the number of people infected with this serious disease has reached more than seven million people from all over the world. In Iraq, the number of people infected has reached more than twenty-two thousand people until April 2020. In this article, we have applied convolutional neural networks (ConvNets) for the detection of the accuracy of computed tomography (CT) coronavirus images that assist medical staffs in hospitals on categorization chest CT-coronavirus images at an early stage. The ConvNets are able to automatically learn and extract features from the medical image dataset. The objective of this study is to train the GoogleNet ConvNet architecture, using the COVID-CT dataset, to classify 425 CT-coronavirus images. The experimental results show that the validation accuracy of GoogleNet in training the dataset is 82.14% with an elapsed time of 74 minutes and 37 seconds.

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Middle East Respiratory Syndrome Coronavirus (MERS CoV): An Emerging Pathogen

Abstract: Abstract:The Middle East respiratory syndrome coronavirus (MERS-CoV)

Cited by 5 publications

References 22 publications

Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-1) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections in pregnancy – An overview

Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-1) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections in pregnancy – An overview

Numerical analysis of factors, pace and intensity of the corona virus (COVID-19) epidemic in Poland

Medical Image Classification for Coronavirus Disease (COVID-19) Using Convolutional Neural Networks

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