Midlatency auditory evoked potential habituation in PTSD

The P1 midlatency auditory evoked potential was studied in patients with Parkinson's disease and compared to that in age-matched controls. Habituation of the potential was determined by using a two-click stimulus paradigm in which the stimuli were presented at 250-, 500-, and 1,000-ms interstimulus intervals. Results showed that habituation of the P1 potential had a statistically significant decrease at the 250-ms and 500-ms interstimulus intervals in patients with Parkinson's disease compared to normal controls. The degree of decreased habituation was found to increase with severity of the disease such that stage 5 patients showed greater decreases in habituation compared to stage 4, as did stage 4 compared to stage 3. These findings may be explained by the presence of a dysregulation of sensory processing, possibly by elements of the reticular activating system, including the pedunculopontine nucleus, in Parkinson's disease.

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Sensory gating in chronic posttraumatic stress disorder: reduced auditory p50 suppression in combat veterans

Neylan

Fletcher

Lenoci

et al. 1999

Biological Psychiatry

124

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Midlatency auditory evoked potential habituation in PTSD

Cited by 5 publications

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Reduced sensory gating of the P1 potential in rape victims and combat veterans with posttraumatic stress disorder

Reduced sensory gating of the P1 potential in rape victims and combat veterans with posttraumatic stress disorder

Decreased habituation of midlatency auditory evoked responses in parkinson's disease

Sensory gating in chronic posttraumatic stress disorder: reduced auditory p50 suppression in combat veterans

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