Midterm angiographic assessment of coronary artery bypass grafting without cardiopulmonary bypass

Ömeroğlu, Suat Nail; Kırali, Kaan; Güler, Mustafa; Toker, Mehmet Erdem; İpek, Gökhan; Işık, Ömer; Yakut, Cevat

doi:10.1016/s0003-4975(00)01567-8

Cited by 64 publications

(35 citation statements)

References 20 publications

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“…Although there are different views, it is generally accepted that visceral vasoconstriction during CPB contributes to the development of GIS complications. Some of the studies have shown that heart surgery without CPB provides more myocardial and renal protection and generates minimal inflammatory response compared to heart surgery with CPB (15)(16)(17). As expected, we noted longer duration of surgery and higher number of grafts placed in our CPB group than in our OPCAB group.…”

Section: Discussionsupporting

confidence: 82%

Clinical significance of intestinal type fatty acid binding protein in patients undergoing coronary artery bypass surgery

Camkiran¹,

Dönmez²,

Aldemir³

et al. 2011

Anadolu Kardiyol Derg

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ÖZETAmaç: Çalışmamızın amacı, kardiyopulmoner baypas (KPB) uygulanan ve uygulanmayan (OPCAB) hastalarda intestinal iskemi ile intestinal yağ asidi bağlayıcı protein (I-FABP) arasında ilişki olup olmadığını belirlemektir. Yöntemler: Çalışma prospektif, gözlemsel olarak planlandı. Elektif koroner arter baypas greftleme cerrahisi uygulanacak 50-70 yaşları arasında hastalar ardışık olarak çalışmaya alındı. Kardiyopulmoner baypas uygulanan 35 hasta birinci grup (CPB), uygulanmayan 16 hasta ikinci grup (OPCAB) olarak kabul edildi. Gruplar arası ve grup içi karşılaştırmalar Student's t, Mann-Whitney U, Friedman ve Wilcoxon testleri ile analiz edildi. Bulgular: Kardiyopulmoner baypas uygulanan grubun I-FABP düzeylerinde operasyon sonunda, başlangıca göre anlamlı yükselme olurken (p<0.005), postoperatif 12. ve 24. saatlerde operasyon bitişine göre anlamlı düşme görüldü (sırasıyla p<0.001, p<0.001). Kardiyopulmoner baypas uygulanmayan grupta ise operasyon sonunda operasyon başlangıcına göre yükselme görülürken (p<0.001), postoperatif 24. saatte operasyon başlangıcına göre anlamlı düşme görüldü (p<0.001). Her iki grubun I-FABP düzeyleri cerrahi bitiminde preoperatif değerlere göre anlamlı şekilde yükseldi. Sonuç: Çalışmamız sırasında hiçbir hastamızda intestinal iskemi görülmezken, I-FABP düzeylerindeki değişiklik bize açık kalp cerrahisi geçiren hastalarda intestinal iskemi monitörizasyonunda I-FABP'nin kullanılabileceğini düşündürdü. ABSTRACTObjective: The aim of this study was to determine whether serum levels of intestinal type fatty acid binding protein (I-FABP) are related to intestinal ischemia in patients undergoing coronary bypass surgery. Methods: The study was planned as prospective, observational. Elective coronary artery bypass candidate patients between ages of 50 and 70 were consecutively included in the study. Thirty-five patients scheduled for cardiopulmonary bypass (CPB) were identified as the CPB group and 16 patients not scheduled for CPB were identified as the off-pump coronary artery bypass surgery (OPCAB) group. The variables between and within the groups were analyzed with Student's t, Mann-Whitney U, Friedman and Wilcoxon tests respectively. Results: In both CPB and OPCAB groups, I-FABP level at the end of the operation was significantly higher than that noted at the beginning of the operation (p<0.005). In the CPB group, there was a significant drop in I-FABP from the end of the operation to each of the postoperative time points (12 th hour and 24 th hour) (respectively p<0.001, p<0.001). In the OPCAB group, the I-FABP levels at both postoperative time points were lower than that at the end of the operation (p<0.001), and the level at 24-hour post-surgery was significantly lower than at both the end-of-operation I-FABP value (p<0.001) and the 12-hour post-surgery I-FABP value. Conclusion: Since we have not observed any intestinal ischemia through our research, slight changes of I-FABP measurements make us believe that I-FABP would be a valuable way to monitor for intestinal ischemia in patients w...

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Section: Discussionsupporting

confidence: 82%

Clinical significance of intestinal type fatty acid binding protein in patients undergoing coronary artery bypass surgery

Camkiran¹,

Dönmez²,

Aldemir³

et al. 2011

Anadolu Kardiyol Derg

View full text Add to dashboard Cite

show abstract

“…Ömeroglu et al compared graft patency between OPCAB and conventional CABG at 24-61 months after surgery and found comparable rates for both techniques, and that especially high patency rates when the internal mammary arteries were used. 28 Early graft patency was also satisfactory in the present OPCAB. In our experience, postoperative angiography on the day after diagnosis of perioperative myocardial infarction will reveal a clot-like filling defect in the graft or coronary artery.…”

Section: Circulation Journal Vol66 September 2002mentioning

confidence: 50%

Perioperative Advantages of Off-Pump Coronary Artery Bypass Grafting.

Ishida

Kobayashi

Tagusari

et al. 2002

Circ J

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“…In addition, off-pump enables decreases in blood loss and blood and blood products, length of the intensive care unit stay, and hospital stay. 23,24) Our approach using off-pump had a shorter intubation time, shorter intensive care unit stay, and shorter hospital stay (Table IV). In all patients, we performed CEA before CABG in order to avoid hemodynamic disturbances in the carotid circulation while using the off-pump.…”

Section: Discussionmentioning

confidence: 92%

<b>Simultaneous Carotid Endarterectomy and Coronary Revascularization is Safe Using Either On-Pump or Off-Pump Technique</b>

et al. 2005

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SUMMARYThe appropriate surgical strategy for patients with combined carotid and coronary artery disease remains controversial. We retrospectively compared our surgical results for 2 types of approaches in this disorder.The records of 76 patients consecutively operated on for carotid and coronary artery disease between August 1993 and October 2004 were reviewed. There were 18 males (66.6%) and 9 females (33.3%) in group I. Group II consisted of 35 males (71.4%) and 14 females (28.5%). The patients were divided into two groups: patients with combined off-pump coronary artery bypass and carotid endarterectomy (group I, n = 27), and those with one-stage on-pump coronary artery bypass and carotid endarterectomy (group II, n = 49). Surgical mortality and morbidity and late outcome were compared among the two groups.The average number of grafts was 1.2 ± 0.4, with the average operative time of 3.3 ± 0.3 hours in group I, and 2.3 ± 0.5 grafts with operative time of 4.6 ± 0.4 hours in group II (P < 0.001 and P < 0.001, respectively). There was 1 death (3.7%) in group I and 2 deaths (4.8%) in group II (P = 0.937). No patient from either group I or group II had postoperative stroke. Mean hospital stay was 7.4 ± 1.9 days in group I and 11.3 ± 1.7 days in group II (P < 0.001). At a mean follow-up of 5.5 ± 3.3 years in group I, 1 patient had contralateral carotid endarterectomy (3.7%). Group II had a mean follow-up of 5.2 ± 3.0 years and contralateral carotid endarterectomy was performed in 1 patient (2.0%). There were no late strokes or deaths in either group.Combined coronary artery bypass grafting and carotid endarterectomy using 2 different types of technique is a safe and effective procedure in patients with significant concomitant monolateral carotid and coronary artery disease. (Int Heart J 2005; 46: 783-793)

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Midterm angiographic assessment of coronary artery bypass grafting without cardiopulmonary bypass

Cited by 64 publications

References 20 publications

Clinical significance of intestinal type fatty acid binding protein in patients undergoing coronary artery bypass surgery

Clinical significance of intestinal type fatty acid binding protein in patients undergoing coronary artery bypass surgery

Perioperative Advantages of Off-Pump Coronary Artery Bypass Grafting.

<b>Simultaneous Carotid Endarterectomy and Coronary Revascularization is Safe Using Either On-Pump or Off-Pump Technique</b>

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