Innovative migration governance mechanisms have been rapidly evolving in Latin America in the last two decades. More recently, new policies have emerged to address both longstanding and unexpected pressing issues, such as the vast and sudden flows from Venezuela and Central America. Focusing on two main sub-regions (Central and South America) and five main areas of state involvement (irregular immigration, border control, diaspora engagement policies, multilateral management of intra-regional mobility, and forced migration), we revisit the argument that a distinctive Latin American approach emerged at the turn of the century. We document growing policy divergence across countries and subregions, which is rendering the region increasingly in line with global trends.