Migration of Fluoride in the Mouth

Weatherell, J.A.; Robinson, C.; Ralph, J P; Best, J.S.

doi:10.1159/000260786

Cited by 60 publications

(27 citation statements)

References 7 publications

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“…in the present study was qualitatively similar to that previously de scribed for fluoride [Weatherell et al, 1984. Concentrations at specific sites were very different from those in samples of 'whole' saliva, sometimes greater, often smaller.…”

Section: Discussionsupporting

confidence: 88%

“…Meyer [1969], Weatherell et al [1984] and Primosch et al [1986] have demonstrated this using fluo ride and Jenkins and Krebsbach [1985] described a similar situation in the case of particulate charcoal. Rates of clearance also vary considerably from site to site Britse and Lagerlof, 1987], The combination of these two factors has a marked effect on the way the mouth handles soluble materials.…”

mentioning

confidence: 86%

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Retention of Glucose in Oral Fluid at Different Sites in the Mouth

Weatherell

Strong²,

Robinson³

et al. 1989

Caries Res

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Using glucose as a marker, a detailed study of retention at 5 different sites in the mouth of 1 subject and a less detailed examination of 4 selected sites in the mouths of 10 other subjects revealed site-specific differential patterns of oral retention (or clearance). These patterns seemed independent of sometimes large, absolute day-to-day variations in oral retention which occur in all subjects but appeared to vary somewhat between subjects, probably reflecting slight differences in the anatomy and physiology of the individual mouth. In general, the patterns resembled those recently derived from studies of other oral phenomena such as rates of diffusion out of plaque, fluoride uptake by mineral and hydrogen ion concentrations in plaque. They will dictate the concentrations and thereby influence the activity of all extraneous substances in different regions of the oral cavity and may relate to the site-specific patterns of oral disease.

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Section: Discussionsupporting

confidence: 88%

mentioning

confidence: 86%

Retention of Glucose in Oral Fluid at Different Sites in the Mouth

Weatherell

Strong²,

Robinson³

et al. 1989

Caries Res

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“…1 In newly erupted teeth, the enamel is porous; thus, it dissolves more easily in comparison with adult enamel. 5 A drop in the pH of dental plaque occurs after consuming carbonated drinks, which takes 20 to 30 minutes to get neutralized by saliva. Although a few attacks may not be harmful, a frequent consumption may lead to deleterious effect.…”

Section: 5005/jp-journals-10024-2166mentioning

confidence: 99%

Dissolution of Enamel on Exposure to Various Commercial Beverages Available in India

Panda

Ghosh²,

Pal³

et al. 2017

The Journal of Contemporary Dental Practice

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Aim:The study was aimed to estimate the pH of the commonly available soft drinks in the Indian market and to assess the detrimental effects of the juices and beverages on the tooth surface by measuring the weight loss of the tooth sample. Materials and methods:The study was done with eight different types of commercially available carbonated drink and fruit juices available in the Indian market among which six were carbonated drinks and two were juices. Carbonated drinks experimented were Coca-Cola, Pepsi, Fanta, Mirinda, 7Up and Sprite, and two fruit juices were Tropicana orange juice and real orange juice. Ten different bottles from each category were obtained, and the pH was estimated. Each of the beverages was divided into batch of 10 containers containing the tooth sample. Weight of all samples was measured at 24, 48, 72, 96, and 120 hours with subsequently changing each solution at an interval of 24 hours. Results:The mean pH of the beverages was found ranging from 2.13 ± 0.02 in Pepsi to 3.41 ± 0.02 in Tropicana on opening. The mean pH of water was found to be 6.98 ± 0.01. Among carbonated drinks, the mean weight loss after 24 hours was highest in Coca-Cola and least in 7Up. Tropicana fruit juice had a higher tooth loss than real orange juices. When compared with water, the tooth loss was significantly higher in Coca-Cola after all specified time (hours). Conclusion:The pH of both carbonated drinks and fruit juices was below the critical pH. The weight loss was also seen after every 24 hours in all the carbonated drinks and beverages. The study showed that these commercial beverages are harmful to the tooth structures, and hence, the health professionals play Clinical significance: The change in lifestyle has increased the demand of soft drinks and artificial juice in Indian market. The use of these carbonated drinks and fruit juices causes damage to the tooth structure in all ages, especially in young mass. Our study provides an idea about the deleterious effects of these commercial drinks on dental hard tissues. Dissolution of Enamel on Exposure to Various Commercial

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“…The simulations in figures 4 and 5 indicate just how much the positiondependent contact which has been shown to exist be tween the plaque surface and the saliva [Weatherell et al, 1984[Weatherell et al, , 1986Lecomte and Dawes, 1987] will affect the course of a Stephan curve and the resultant de mineralisation. Lingual intra-oral sites correspond to values of FILMTIME in the range 0-0.5 min, while those for buccal sites, depending on location, corre spond to values in the range 2-4 min.…”

Section: Simulation O F the Caries Processmentioning

confidence: 99%

“…Weatherell et al [1984Weatherell et al [ ,1986 placed tab lets at different sites in the mouth, while Lecomte and Dawes [1987] fixed a small gel-containing reservoir to the teeth at various sites. The rates of dissolution of the tablet, or clearance of solute from the gel, were then used as indicators of the rate of exchange be tween the plaque surface at this site and the bulk sa liva.…”

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confidence: 99%

Effect on a Cariogenic Challenge of Saliva/Plaque Exchange via a Thin Salivary Film Studied by Mathematical Modelling

Gh¹

1990

Caries Res

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Computer models can be powerful tools for studying complex interacting processes. The computer model of events in dental plaque during a cariogenic challenge described here simulates diffusion and metabolism of substrate, plus coupled diffusion/reaction of fourteen other species, charged and uncharged, including acidic metabolic products and fixed buffers. Its extension to deal with the effects of poor contact with bulk saliva when the plaque is presumed covered by a thin salivary film is here considered. Site-specific mixing rates between film and salivary pool were modelled phenomenologically, using data from the literature. Fast mixing was assumed during an initial carbohydrate intake phase (2 min sugar rinse), followed by site-dependent mixing and logarithmic clearance. The analysis also suggested a possible way of estimating local salivary film thickness. Increasing the halving time for exchange between film and bulk saliva was shown to prolong the pH minimum greatly, and to increase mineral loss. The respective roles of fixed buffers as stores of protons and of mobile buffers (especially bicarbonate) as exporters of protons from the inner plaque were emphasised.

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Migration of Fluoride in the Mouth

Cited by 60 publications

References 7 publications

Retention of Glucose in Oral Fluid at Different Sites in the Mouth

Retention of Glucose in Oral Fluid at Different Sites in the Mouth

Dissolution of Enamel on Exposure to Various Commercial Beverages Available in India

Effect on a Cariogenic Challenge of Saliva/Plaque Exchange via a Thin Salivary Film Studied by Mathematical Modelling

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