Migration of Tinuvin P and Irganox 3114 into milk and the corresponding authorised food simulant

Abstract

Migration of Tinuvin P (UV stabiliser) and Irganox 3114 (antioxidant) from high-density polyethylene (HDPE) was studied. HDPE pieces were soaked in either milk (1.5% or 3.5% fat content) or 50% (v/v) ethanol-water mixture - the food simulant for milk as specified in Regulation No. 10/2011/EC. The obtained extracts were analysed by LC-MS/MS. For statistical assessment variography was used. It proved to be a useful tool for making a distinction between the early migration range and the equilibrium, despite the variance of the data. Regulation No. 10/2011/EC specifies 10 days of contact time for milk at 5°C. Our experiments with the food simulant with 24 dm(2) kg(-1) surface/mass ratio showed that both Tinuvin P and Irganox 3114 need less than 1 h to reach equilibrium. Furthermore, 10-day experiments with daily sampling showed that these additives are stable in milk, as well as in the food simulant. The effect of the concentration of the additives in HDPE was studied in the 0.01-5% (m/m) range. For both Tinuvin P and Irganox 3114 and all three extractants the migrated amount became independent of the concentration of the additive in the HDPE approximately at 1% (m/m). For Tinuvin P the food simulant gave a close estimate for the milk samples. However, using the food simulant for modelling the migration of Irganox 3114 into milk gave an overestimation with a factor of minimum 3.5. In the case of Tinuvin P special care must be taken, since the recommended amount in the HDPE can result in additive concentrations near or even over the specific migration limit (SML). However, Irganox 3114 cannot reach the SML either in milk or in the food simulant.

Ion-Mobility Quadrupole Time-of-Flight Mass Spectrometry: A Novel Technique Applied to Migration of Nonintentionally Added Substances from Polyethylene Films Intended for Use as Food Packaging

“…7 Recently, the importance of analyzing MOSH, POSH, and MOAH 8 has been emphasized. Nonvolatile compounds typically analyzed by LC-MS include stabilizers (tinuvins or chimassorbs 9 ), antioxidants (Irgafos 168, Irganox 1010, Irganox 1076, 9 and Irganox 3114 10 ), plasticizers (phthalates, 11 linear alkanamides, and bisphenol A), and surfactants nonylphenols. 12,13 In addition, the use of Raman technology to detect Uvitex OB 14,15 has been described in relation to this application area.…”

Effect of crystallinity on the migration of plastic additives from polylactic acid-based food contact plastics

“…Garamhegyi et al (2020) and Hatvani et al (2014) analysed the spatial autocorrelation of the level and the quality of shallow groundwater. Bodai et al (2015), Kirchkeszner et al (2022) and Petrovics et al (2022) used variography to obtain the necessary contact time to reach a steady-state. Using this method, a range could be determined beyond which the observations were uncorrelated.…”

Determination of Volatile Migrants from Breast Milk Storage Bags

“…Numerous studies have investigated migration from food packaging made with this polymer, both as a monolayer material and as part of multilayer packaging structures. Different kind of compounds have been found in migration: antioxidants such as Irganox 3114 (Bodai et al, 2015), Irganox 1010 and Irganox 1076 (Sungur &Tunur, 2020), Ethanox 330 andIrgafos 168 (Dopico-García et al, 2003); fluorescent whitening agents (FWAs) (Ji et al, 2020); UV-ink photoinitiators such as Irgacure 819 or Darocure 1173 (Zhang et al, 2016); and plasticizers such as diisobutyl phthalate (DIBP) and dibutyl phthalate (DBP) (Liu et al, 2020)(Di Bella et al, 2014. Other authors have specifically studied the migration of non-intentionally added substances (NIAS) from polyethylene and other polyolefins such as polypropylene (Su et al, 2020) (Vera et al, 2019) (Vera et al, 2020) (Chen et al, 2021).…”