Mild Cognitive Impairment, Screening, and Patient Perceptions in Heart Failure Patients

Gallagher, Robyn; Sullivan, A.; Burke, Rhonda; Hales, S.; Gillies, G.; Cameron, Jan; Saliba, Bernard; Tofler, Geoffrey H.

doi:10.1016/j.cardfail.2013.08.001

Cited by 37 publications

(24 citation statements)

References 32 publications

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“…The finding of symptoms in multiple cognitive domains is consistent with what has been found in earlier research, 2,20,21,32 with the exception of this study lacking evidence for executive impairment. The raw scores on the executive test (Stroop III) did, however, differ quite clearly between control subjects and patients, and the P value could be considered to be at borderline significance.…”

Section: Discussionsupporting

confidence: 93%

“…20,32 Cameron et al 28 and Hajduk et al 21 found almost as high prevalences of cognitive impairment in HF patients: 79% and 75%, respectively. In the latter study the patients, however, were hospitalized.…”

Section: Discussionmentioning

confidence: 96%

“…The impairments were mainly in the memory and executive domains. 20 In another study HF patients displayed memory, processing speed, and executive impairment, executive impairment being the most common impairment. 21 In a recent study, obesity was found to be associated with cognitive performance in men with HF, who showed attention and executive deficits.…”

mentioning

confidence: 98%

See 2 more Smart Citations

Frequent Mild Cognitive Deficits in Several Functional Domains in Elderly Patients With Heart Failure Without Known Cognitive Disorders

Nordlund

Berggren

Holmström

et al. 2015

Journal of Cardiac Failure

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Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 96%

See 1 more Smart Citation

Frequent Mild Cognitive Deficits in Several Functional Domains in Elderly Patients With Heart Failure Without Known Cognitive Disorders

Nordlund

Berggren

Holmström

et al. 2015

Journal of Cardiac Failure

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“…The cumbersome methodology used in many research studies cannot readily be applied in HF clinical practice. 26,27 …”

Section: Discussionmentioning

confidence: 99%

Usefulness of Cognitive Dysfunction in Heart Failure to Predict Cardiovascular Risk at 180 Days

Gelow

Mudd

Chien

et al. 2015

The American Journal of Cardiology

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Cognitive dysfunction is common among heart failure (HF) patients. Despite the high prevalence and the adverse associations of cognitive dysfunction in HF, the prognostic implications remain poorly understood. We sought to determine the influence of cognitive dysfunction, identified using the Montreal Cognitive Assessment (MoCA), on 180-day cardiovascular events. We analyzed data on 246 participants in an observational cohort study of adults with HF. The interview-format MoCA was administered to all participants. Time to first cardiovascular event was assessed as a cumulative end point during the 180 days after enrollment. Cox proportional hazards modeling were used for analysis of time to first event. The MoCA score was < 26 for 91 (37%) patients. Patients with a MoCA score <26 were more likely to have a cardiovascular event at 180 days. MoCA score < 26 remained an independent predictor of cardiovascular event risk at 180 days when adjusted for the Seattle Heart Failure Model Score and the Charlson Comorbidity Index (Hazard Ratio 1.7, 95% Confidence Interval 1.1-2.6, p = 0.03). In conclusion, in HF patients, cognitive dysfunction identified with a MoCA score of <26 is associated with increased risk of cardiovascular events at 180 days.

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“…Cognitive performance should be evaluated routinely in persons with HF, particularly when first diagnosed and when changes in treatment regimen occur, and with worsening disease severity since these events have been shown to precede changes in cognition [5, 6]. Currently, there are no clinical guidelines to provide recommendations when cognitive screening should be initiated in HF or the best measure and threshold to use for this purpose [69]. If a person with HF screens positive for CI, there should be additional neuropsychological testing conducted to determine type and level of impairment as well as resources available to optimally support the person to be functionally independent of as long as feasible.…”

Section: Implications and Future Directionsmentioning

confidence: 99%

Aerobic Exercise as an Adjunct Therapy for Improving Cognitive Function in Heart Failure

Gary

Brunn

2014

Cardiology Research and Practice

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Persons with heart failure (HF) are typically older and are at a much higher risk for developing cognitive impairment (CI) than persons without HF. Increasingly, CI is recognized as a significant, independent predictor of worse clinical outcomes, more frequent hospital readmissions, and higher mortality rates in persons with HF. CI can have devastating effects on ability to carry out HF effective self-care behaviors. If CI occurs, however, there are currently no evidence based guidelines on how to manage or improve cognitive function in this population. Improvement in cognition has been reported following some therapies in HF and is thought to be the consequence of enhanced cerebral perfusion and oxygenation, suggesting that CI may be amenable to intervention. Because there is substantial neuronal loss with dementia and no effective restorative therapies, interventions that slow, reverse, or prevent cognitive decline are essential. Aerobic exercise is documented to increase cerebral perfusion and oxygenation by promoting neuroplasticity and neurogenesis and, in turn, cognitive functioning. Few studies have examined exercise as a potential adjunct therapy for attenuating or alleviating cognitive decline in HF. In this review, the potential benefit of aerobic exercise on cognitive functioning in HF is presented along with future research directions.

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Mild Cognitive Impairment, Screening, and Patient Perceptions in Heart Failure Patients

Cited by 37 publications

References 32 publications

Frequent Mild Cognitive Deficits in Several Functional Domains in Elderly Patients With Heart Failure Without Known Cognitive Disorders

Frequent Mild Cognitive Deficits in Several Functional Domains in Elderly Patients With Heart Failure Without Known Cognitive Disorders

Usefulness of Cognitive Dysfunction in Heart Failure to Predict Cardiovascular Risk at 180 Days

Aerobic Exercise as an Adjunct Therapy for Improving Cognitive Function in Heart Failure

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