To the Editor:Vitamin D insufficiency has become recognized as a common phenomenon among ambulatory and hospitalized adults (1). Vitamin D is associated with increased risk of many chronic illnesses including cancer, hypertension, diabetes, and osteoporosis (2). The best marker of vitamin D status is the serum 25-hydroxyvitamin D concentration (1). Many factors influence circulating 25-hydroxyvitamin D levels including race, season, body mass index, and age (1).The prevalence of vitamin D insufficiency has not been well characterized in US war veterans. McMurtry and colleagues found that most veterans living in nursing homes have vitamin D insufficiency (3). We sought to determine the prevalence of vitamin D insufficiency in ambulatory US war veterans seen at the Atlanta VA Medical Center. We were also interested in which physicians were screening for vitamin D insufficiency and how vitamin D insufficiency was being treated.The study was approved by the Emory University Institutional Review Board and the Atlanta VA Medical Center Research and Development Committee. Using the VA computerized patient record system, we collected all 25-hydroxyvitamin D levels that were measured in the fall month of September 2006 and the spring month of March 2007. We collected demographic information including age, sex, body mass index, race, and the specialty of the physician ordering the test. We determined the number of individuals who were vitamin D insufficient defined as a 25-hydroxyvitamin D concentration less than 30 ng/mL. We reviewed pharmacy records to determine if and how the vitamin D insufficiency was treated.We found that 25-hydroxyvitamin D was measured 136 and 226 times in the months of September and March, respectively. There were no differences in age, sex, and body mass index in the fall and spring groups ( Table 1). As expected, mean 25-hydroxyvitamin D levels were statistically lower in the spring compared with the fall, and there was a higher prevalence of vitamin D insufficiency in the spring (Table 1)
NIH-PA Author ManuscriptNIH-PA Author Manuscript NIH-PA Author Manuscript subjects had a higher prevalence of vitamin D insufficiency in the spring compared to the fall in contrast to black subjects who did not have statistically significant seasonal variation in the prevalence of vitamin D insufficiency. There were differences in the specialty of the physician ordering the 25-hydroxyvitamin D level with nephrologists being the most common physician group testing for vitamin D status. Only about 30% of participants who were deemed to have vitamin D insufficiency were prescribed more than 1000 IU of vitamin D. Almost half of the participants did not receive any treatment for vitamin D insufficiency.In conclusion, we found that vitamin D insufficiency was highly prevalent in veterans and that many veterans either did not receive treatment for vitamin D insufficiency or received inadequate amounts of vitamin D replacement to restore vitamin D status to normal. These findings further underscore the urgent need t...