Milia cysts along the nasal groove in a child

Abstract

The occurrence of transverse linear milia cysts over the dorsum of the nose in an 11-year-old girl is described. Two younger sisters of the proband had a conspicuous nasal groove at the same site without milia. The anatomical basis and the pathogenesis of the so-called 'transverse nasal crease' are reviewed.

Milia: A review and classification

“…Although benign primary milia of children and adults usually occur on the cheeks and eyelids, there are several reports of benign primary milia in unusual locations, including the nasal crease, [18][19][20][21][22] vulva, 23,24 and areola. 25,26 Of particular interest are nasal crease milia.…”

Atypical "allergic crease"

“…1 Additionally, the formation of milia has also been described, with pathologic evaluation revealing an epidermal cyst. 5 It has been suggested that the rupture of these cysts leads to keratin penetration into the dermis and the formation of acneiform lesions, histopathologically showing foreign body granulomas with inflammation. 6 These lesions have been termed "pseudoacne of the nasal crease".…”

“…Although it is a very prevalent condition, appearing in 7% of schoolchildren with nasal symptoms and signs of allergic rhinitis, 4 the skin manifestations which accompany this condition have been only sparsely reported. 5,6 We present a patient with small cornified papules which developed along the allergic crease.…”

Transverse Nasal Line Associated with Congenital Persistent Milia

“…Two cases of congenital persistent milia associated with a transverse nasal line have been reported so far [3,4]. In both patients, cystic lesions were almost exclusively located along the nasal line, although in 1 patient a few similar lesions on the face were also noted [4].…”

“…It is important to recognize the nasal line as a localizing factor for comedones [2] and milia [3,4]. We describe the occurrence of congenital persistent milia associated with a transverse linear line in a child.…”