Milia‐Like Idiopathic Calcinosis Cutis

Abstract

Milia-like idiopathic calcinosis cutis is a rare entity. Only 17 cases have been reported so far. Two-thirds of these have been associated with Down syndrome. We report the fifth case occurring in a child without Down syndrome. Milia-like idiopathic calcinosis cutis has long been regarded as a peculiar subtype of idiopathic calcinosis cutis. The pathogenesis of the disorder remains unclear.

Milia: A review and classification

“…An uncommon variant of calcinosis cutis is milia-like idiopathic calcinosis cutis ( Fig 11). 178,179 Patients are often children with Down syndrome and they have solitary or multiple lesions. Scrotal calcinosis may represent calcified milia or syringomas.…”

Caso para diagnóstico

“…3,4 This rare presentation, first described in 1978, has not had more than 20 described cases in the medical literature and among them two thirds occurred in patients born with trisomy 21. 5 Idiophatic calcinosis, different from the other forms, does not present pathogenesis or defined casual factor, it has no relation with the increase of calcium and serial phosphorus, trauma or exogenous infusion of calcium.…”

“…4 As for idiopathic calcinosis, the expected conduct is the ideal one once the majority of them involute throughout adolescence and adulthood. 1,5 The dificulty in defining the limits of the lesion in the area and the possibility that a surgical trauma generates local recurrence turns the excisional procedure a rare choice for approaching the problem.…”

“…4 Effective member of the SBD (Brazilian Society of Dermatology); substitute professor at Pedro Ernesto University Hospital, dermatologist at Jesus Municipal Hospital ; head of the ambulatory dermatologic pediatrics of Prof. Azulay Institute of Dermatology -Santa Casa de Misericórdia do Rio de Janeiro -Rio de Janeiro (RJ), Brazil. 5 Doctorate degree (Dermatology); assistant professor of Dermatology and responsable for the sector of Dermapathology at Pedro Ernesto University HospitalRio de Janeiro (RJ), Brazil.…”

Idiopathic Calcinosis Cutis in a Child: Chemical Composition of the Calcified Deposits

“…Idiopathic CC is also defined by abnormal deposits of calcium salts in the dermis with typical localization to one general area. Moreover, idiopathic calcification is different from dystrophic, metastatic or iatrogenic calcification, as it manifests in normal tissue, without tissue damage, but also displays normal calcium and phosphorus levels [3,4]. …”