Miliaire tuberculeuse au Mali pendant la décennie 2000–2009

Toloba, Y.; Diallo, S.; Maïga, Yacouba; Sissoko, B.F.; Keita, Bourama

doi:10.1016/j.pneumo.2011.06.010

Cited by 6 publications

(12 citation statements)

References 9 publications

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“…Patients with miliary TB represented 13% of patients with pulmonary TB diagnosed over 2 years in the Department of Internal Medicine and Infectious Diseases of the Kiffa Regional Hospital Center. The proportion of miliary TB in our study is lower than that observed in other studies carried out in Africa, notably in other countries in the region, including Tunisia [7], Morocco [6], Mali [4], and Senegal [5]. The male:female sex ratio was higher in our study than that observed in other African countries [5], [6], [8].…”

Section: Discussioncontrasting

confidence: 83%

“…In our series, BCG vaccination scar was found in only two cases (8%). This observation tends to support the data in the literature that BCG efficacy is well established in the prevention of serious forms of TB, such as miliary TB and TB meningitis [4], [13]. However, confirmation of BCG efficacy is difficult to demonstrate in a context where vaccination coverage is still insufficient in many countries where TB is highly prevalent.…”

Section: Discussionsupporting

confidence: 74%

“…The seroprevalence of HIV infection in our study was 17%. HIV-TB co-infection is a well-established fact, documented and reported by several authors [2], [4], [5], [6], [9], especially for pulmonary TB.…”

Section: Discussionmentioning

confidence: 91%

“…Miliary TB is a potentially fatal form of TB that results from massive lymphohematogenous dissemination of Mycobacterium tuberculosis [1], [2], [3]. The incidence of miliary TB in relation to all forms of TB is between 0.15% and 10%, depending on the studies conducted by different authors [1], [4], [5]. Its mortality rate has been reported to lie between 13% and 25%, and even up to 65% in patients requiring mechanical ventilation [3], [6].…”

Section: Introductionmentioning

confidence: 99%

“…Its mortality rate has been reported to lie between 13% and 25%, and even up to 65% in patients requiring mechanical ventilation [3], [6]. Miliary TB still faces diagnostic difficulties even in developed countries, sometimes leading to delays in initiating appropriate treatment, thus compromising the vital prognosis [4], [6], [7]. No studies on the description of clinical aspects of miliary TB have been conducted in Mauritania.…”

Section: Introductionmentioning

confidence: 99%

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Miliary tuberculosis and acute respiratory distress syndrome

Boushab

Basco

2019

Journal of Clinical Tuberculosis and Other Mycobacterial Diseas

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BackgroundMiliary tuberculosis is a serious and uncommon form of tuberculosis due to hematogenous dissemination of Mycobacterium tuberculosis.ObjectiveThis study aimed to describe the epidemiological and clinical features of miliary tuberculosis.Patients and MethodsData were collected from clinical files between August 2016 and July 2018.ResultsIn 2 years, 24 cases were recorded, representing a proportional morbidity of 13%. Among them, 71% were smokers and 38% had diabetes. The presence of a BCG vaccination scar was observed in 2 patients (8%). Human immunodeficiency virus (HIV) serology was positive in 4 cases (17%). The symptomatology was dominated by: fever (100%), cough (83%), and chest pain (79%). Radiological images with micronodular opacities were the most common (54%), followed by macronodular densities (33%), and reticulonodular densities (13%). The evolution was favorable in 77%, with no patient lost to follow-up, but 7/24 (29%) died, either before the initiation of therapy (n = 2) or during therapy (n = 5).ConclusionMiliary tuberculosis is an acute and severe form of life-threatening tuberculosis. It requires a prompt and accurate diagnosis and treatment. An improved accessibility to early diagnosis and treatment and prevention of TB infection should reduce its prevalence.

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