Milk carton with integrated paper‐based microfluidics for milk quality rapid test

Abstract

This study integrated paper‐based microfluidic device on a milk carton for a rapid milk quality check. The microfluidic device was printed on the outer surface of milk carton using commercial wax printer. The testing process is fully automatic, after apply one drop of milk on the loading point, milk was driven by capillary force in the porous paper fiber in wax‐defined microchannels to reach the preload reactants for chromogenic reaction. The proposed integration method provides a simple, low cost and rapid onsite milk quality check technique for milk consumers, and also have wide potential applications in food industry. Practical applications Microfluidics has been widely used in the chemical and biological field for analysis or synthesis, in this research, the microfluidic devices were integrated on the outer surface of a milk carton for a rapid and low‐cost milk quality test, and the test result could be easily read using mobile phone app. The proposed research is of significant application prospect in food industry for rapid and onsite food quality test using the microfluidic devices integrated on paper packaging. The fabrication method of the microfluidic devices proposed in this research using wax printing is also low cost and nontoxic, and could be easily integrated with the current paper packaging production line.

A Complexity-Efficient High Resolution Propagation Parameter Estimation Algorithm for Ultra-Wideband Large-Scale Uniform Circular Array

“…The presented antenna gains and half-power beamwidths in Table II are the values evaluated in the considered frequency range 28-30 GHz. Readers may refer to [37] for the detailed description of the measurement system including the calibration, etc. 1 The Fraunhofer distance, i.e.…”

Recent Advances in Microfluidic Devices for Contamination Detection and Quality Inspection of Milk

“…Milk quality inspection generally involves checking the milk fat, milk protein (lactoferrin), lactose, total solids, somatic cell count, viscosity, and specific DNA sequences. Various microfluidic devices have been proposed for evaluating the lactoferrin [ 113 ], lactose [ 114 ], somatic cell count [ 115 ], adulterants [ 116 , 117 ] viscosity [ 118 ], and specific DNA sequences [ 119 ] of milk samples. For example, Wang et al [ 113 ] developed a lab-on-paper immunoassay device for the detection of bovine lactoferrin in which a microfluidic immunoassay strip was coated with lactoferrin antigen as the test line and anti-mouse IgG as the control line (see Figure 5 c).…”

“…The linear detection range for lactoferrin in milk samples was found to be 9.76–625 ng/mL with a LOD of 0.01 ng/mL. Fan et al [ 116 ] developed a milk carton with an integrated microfluidic lab-on-paper colorimetric device for rapid milk quality testing. As shown in Figure 5 d, the microfluidic device was printed on the outer surface of the milk carton and was coated with a detection reagent in the reaction zone.…”

Microbiological stability and general sensory acceptance of microfiltered skim milk with agave fructans of a high degree of polymerization added

“…The consumption of fresh unpasteurized dairy products is a tradition in Mexico. Most of these products (including cheese) represent a health risk for the possible contamination of pathogens, such as Salmonella spp., Campylobacter , Brucella , and diarrheic Escherichia coli O157:H7, which are naturally present in cow's udders and milking facilities (Fan, Wang, Liu, Zhang, & Zhang, 2018; Guzmán‐Hernández et al, 2016; Hull‐Jackson, Mota‐Meira, & Adesiyun, 2019). The main problem in the processes of preservation of fresh/raw milk is to achieve a balance between the reduction of bacteria and the retention of nutrients and sensory characteristics.…”