Mindfulness-Based Cognitive Therapy and a Group Version of the Cognitive Behavioral Analysis System of Psychotherapy for Chronic Depression: Follow-Up Data of a Randomized Controlled Trial and the Moderating Role of Childhood Adversities

Mindfulness-based cognitive therapy for patients with chronic, treatment-resistant depression: A pragmatic randomized controlled trial

“…Moderating effects of childhood trauma and severity of baseline symptoms were previously found in recurrent depressed patients (Ma & Teasdale, 2004; Williams et al., 2014). However, recent studies on MBCT in chronic or pharmacoresistant depression found no moderating effect of these variables (Eisendrath et al., 2016; Michalak et al., 2016), which is in line with our findings. Taken together, these results indicate that rumination might be an important moderator in chronic, treatment‐resistant depression, while levels of childhood trauma and severity of depressive symptoms at baseline appear to be of less influence.…”

“…In line with these findings, in a recent randomized controlled trial (RCT) of Eisendrath et al (2016) in treatmentresistant depressed patients, MBCT was demonstrated to be superior to an active control group matched on treatment intensity. However, partly contrasting results were found by Michalak, Probst, Heidenreich, Bissantz, and Schramm (2016) in an RCT comparing MBCT with Cognitive Behavioural Analysis System of Psychotherapy (CBASP) and treatment-as-usual (TAU) in chronically depressed patients. CBASP is a psychological treatment with a strong interpersonal orientation that focuses on overcoming the learned helplessness of the patient by teaching patients that their own behavior affects others and themselves (McCullough, 2003).…”

“…Michalak et al. (2016) concluded that MBCT was inferior to CBASP, and MBCT was superior to TAU only at one treatment site.…”

Does Childhood Maltreatment Moderate the Effect of the Cognitive Behavioral Analysis System of Psychotherapy versus Supportive Psychotherapy in Persistent Depressive Disorder?

“…Our results extend earlier findings by Nemeroff et al [2], because the CM assessment used in their study did not include emotional abuse. Our results are also in agreement with a study by Michalak et al [10], suggesting that CM is associated with a less favorable course in chronic depressive subjects only if they received treatment as usual but not if they were treated with CBASP or mindfulness-based cognitive therapy. It should be noted, however, that the findings of a study demonstrating that CBASP was more effective than medication in patients reporting CM [2] could not be replicated in a more recent, considerably smaller, trial [8].…”

Childhood Maltreatment in Women with Borderline Personality Disorder, Chronic Depression, and Episodic Depression, and in Healthy Controls

“…First studies indicate that CM may moderate the course of depression in favor of a specific psychotherapy (like the cognitive behavioral analysis system of psychotherapy, CBASP) compared to medication [9] or treatment as usual [10]. Therefore, CM may support the indication of a disorder-tailored psychotherapy in which these early experiences and the interpersonal problems are appropriately addressed and treated, i.e., like in CBASP for CD and in dialectic behavioral therapy for BPD.…”