Mindfulness in the Maintenance of Cognitive Capacities in Alzheimer’s Disease: A Randomized Clinical Trial

Quintana-Hernández, Domingo J.; Miró-Barrachina, María Teresa; Ibáñez-Fernández, Ignacio J.; Santana-del-Pino, Ángelo; Montesdeoca, María del Pino Quintana; Vera, Bienvenida Rodríguez-de; Morales-Casanova, David; Pérez-Vieitez, María del Carmen; Rodrı́guez-Garcı́a, Javier; Bravo-Caraduje, Noelia

doi:10.3233/jad-143009

Cited by 72 publications

(74 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Mixed trials are also inconclusive when analyzing the length of the trial. A 2-year trial [68] achieved good final outcomes in several dimensions, but also a 2-week trial [61] seemed to be very effective. On the other hand, some other short trials do not have any efficacy, so the length does not seem to be an important aspect when analyzing intervention efficacy.…”

Section: Discussionmentioning

confidence: 99%

“…All effects found showed better scores for the patients that received intervention, compared to the control group. The 2-year study [68] showed significant efficacy in all measured outcomes, except for orientation, remote memory, calculation, and tactile and visual perception. Shorter studies, like the 2-month study, showed also relevant efficacy in all the measured outcomes.…”

Section: Mixed Trialsmentioning

confidence: 99%

“…Therapy was heterogeneous in number, duration and length of the sessions. For example, Quintana-Hernández et al [68] conducted treatment for 2 years, with 3-weekly sessions (90 min per session), while Buettner et al [60] only conducted treatment for 4 weeks, two times a week (60 min per session). Control conditions varied also between studies, from sham intervention [67] to usual care [68] to a rivastigmine transdermal patch as control condition [61].…”

Section: Mixed Trialsmentioning

confidence: 99%

“…Some studies included elderly at risk for dementia [67], elderly with mild cognitive impairments [63,70], patients with mild to moderate dementia [64,66], moderate to severe dementia [69], diagnosed with Alzheimer disease [61,62,64,65,68], or a combination of these patients [59,60]. Assessment of cognitive impairment was mostly conducted with the MMSE, but also with other measurements (ADAS-Cog, Clinical Dementia Ranking -CDR).…”

Section: Mixed Trialsmentioning

confidence: 99%

See 3 more Smart Citations

Cognitive Therapy for Dementia Patients: A Systematic Review

Carrión

Folkvord

Anastasiadou

et al. 2018

Dement Geriatr Cogn Disord

View full text Add to dashboard Cite

Background: Cognitive therapy is a well-established intervention for treating elderly suffering from dementia. In particular, reality orientation and skills training seem to be effective interventions for reversing cognitive impairment among elderly, although findings are inconclusive. Therefore, a systematic update of the existing evidence of cognitive therapy for people suffering from dementia is needed. Aim: To review existing scientific evidence regarding the efficacy of cognitive therapies for elderly suffering from dementia. Methods: Studies were retrieved from several bibliographic databases (January 2009 to December 2017) with prespecified selection criteria, data extraction, and methodological quality assessment. Results: In total, 10 reality orientation, 25 skills training, and 12 mixed trials were identified as meeting the inclusion criteria and were systematically reviewed. Results from reality orientation trials showed minor effects for cognitive assessments, while skills training trials and mixed trials showed contradicting effects on cognition. Effects on other outcomes (e.g., daily functioning, depression, language) were limited or not found. Conclusions: Skills training trials and mixed trials seem to affect cognitive impairment in a positive way, although the results are inconclusive. Comparison between studies was difficult due to differences in form of intervention. Because findings are inconclusive, more structuralized and comparable randomized controlled trials are needed.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Mixed Trialsmentioning

confidence: 99%

Section: Mixed Trialsmentioning

confidence: 99%

Section: Mixed Trialsmentioning

confidence: 99%

See 2 more Smart Citations

Cognitive Therapy for Dementia Patients: A Systematic Review

Carrión

Folkvord

Anastasiadou

et al. 2018

Dement Geriatr Cogn Disord

View full text Add to dashboard Cite

show abstract

“…A review by Jesse Russell-Williams et al analyzed ten different studies, comprising of six studies on mindfulness (mindfulness-based stress reduction, MBSR), three studies on Kirtan Kriya (KK) meditation, and one study on mindfulnessbased Alzheimer's stimulation (MBAS) [136]. The analysis highlights that the investigation by Quintana-Hernandez et al, spanning over two years, shows that mindfulness can be used as a non-pharmacological method to delay cognitive deterioration in case of mild to moderate AD patients, a study based on MBSR and KK [137]. Newberg et al reported that practicing KK for eight weeks in case of subjective memory loss due to AD or mild cognitive impairment resulted in a significant increase in cerebral blood flow (CBF) within the frontal lobe and right superior parietal lobe [138].…”

Section: Stress Meditation and Admentioning

confidence: 99%

Nature’s Derivative(s) as Alternative Anti-Alzheimer’s Disease Treatments

Sharma

Kumar

2019

ADR

View full text Add to dashboard Cite

Alzheimer's disease (AD), the 'Plague of Twenty-First Century,' is a crippling neurodegenerative disease that affects a majority of the older population globally. By 2050, the incidence of AD is expected to rise to 135 million, while no treatment(s) that can reverse or control the progression of AD are currently available. The treatment(s) in use are limited in their ability to manage the symptoms or slow the progression of the disease and can lead to some severe side effects. The overall care is economically burdensome for the affected individuals as well as the caretakers or family members. Thus, there is a pressing need to identify and develop much safer alternative therapies that can better manage AD. This review discusses a multitude of such treatments borrowed from Ayurveda, traditional Chinese practices, meditation, and exercising for AD treatment. These therapies are in practice since ancient times and reported to be beneficial as anti-AD therapies. Ayurvedic drugs like turmeric, Brahmi, Ashwagandha, etc., management of stress by meditation, regular exercising, and acupuncture have been reported to be efficient in their anti-AD usage. Besides, a combination of vitamins and natural dietary intakes is likely to play a significant role in combating AD. We conclude that the use of such alternative strategies will be a stepping-stone in preventing, treating, curing, or managing the disease.

show abstract