Mineral and trace metal supplement for use with synthetic diets based on comminuted chicken.

Current status of zinc in health and disease states.

“…This may be the case in vegans, vegetarians (Bodzy et al, 1977), low socioeconomic groups subsisting on low meat diets (Hambidge et al, 1972, and patients with chronic renal disease on low protein diets (Rose and Willden, 1972). Synthetic diets used in the treatment of children with inborn errors of metabolism and dietary intolerances require zinc supplements (Alexander et al, 1974;Thorn et al, 1978), and this may be the case for soya-based infant formulae although it has not yet been assessed. It is conceivable that the ingestion of texturised vegetable protein meat extenders and other novel protein sources, or calorie-controlled diets may be at risk.…”

Some nutritional aspects of trace metals

“…An amended mixture, providing a fourfold increase in the intake of zinc, a doubling of the copper intake, and a 25 % increment in that of iron, with manganese provided separately at 1.1 ~tmol (60gg)/kg body weight per day, was found to be satisfactory for synthetic diets based on crystalline amino acids (Lawson et al, 1977). Later, this supplement with manganese incorporated in the mineral mixture was found to be appropriate for infants receiving comminuted chicken for the management of protracted diarrhoea (Thorn et al, 1978). Interestingly, the mean zinc intake (5.97 pmol/kg body weight per day) of the latter group was greater than that of healthy children (4.64 gmol/kg body weight per day) but, nevertheless, they were in negative balance for the metal.…”

“…The amended supplement provided 11.6 gmol/kg body weight zinc per day and a positive balance. The reason for this reduced bioavailabitity of zinc from a diet based on animal protein is not clear but, with the wisdom of hindsight, it is noteworthy that all the patients had been on iron supplements before or during the balance studies (Thorn et al, 1978).…”