Mineral and vitamin content of mature breast milk of Saudi lactating mothers

Al‐Othman, Abdulaziz; El-Fawaz, Hanan A.; Hewedy, Fawzy M.; Al‐Khalifa, Abdulrahman S.

doi:10.1080/03670244.1996.9991469

Cited by 6 publications

(1 citation statement)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Mean total thiamine in milk samples from Maela camp (755 nmol/L) was higher than reported for well-nourished Spanish (590 nmol/L) [17] and vitamin supplemented (1.7 mg B1/day) American mothers (706, 676 nmol/L) [15] , [16] . Similar high amounts of thiamine were measured in mature breast-milk of Saudi women (800 nmol/L) [27] . The significant improvement in breast-milk thiamine collected 10 years apart from Maela refugee camp women suggests that the implementation of thiamine as a general pregnancy supplement (not only for symptomatic women) and in lactation at 100 mg/day not 10 mg/week was highly effective in this setting.…”

Section: Discussionsupporting

confidence: 73%

Thiamine Diphosphate in Whole Blood, Thiamine and Thiamine Monophosphate in Breast-Milk in a Refugee Population

et al. 2012

View full text Add to dashboard Cite

Background The provision of high doses of thiamine may prevent thiamine deficiency in the post-partum period of displaced persons. Methodology/Principal Findings The study aimed to evaluate a supplementation regimen of thiamine mononitrate (100 mg daily) at the antenatal clinics in Maela refugee camp. Women were enrolled during antenatal care and followed after delivery. Samples were collected at 12 weeks post partum. Thiamine diphosphate (TDP) in whole blood and thiamine in breast-milk of 636 lactating women were measured. Thiamine in breast-milk consisted of thiamine monophosphate (TMP) in addition to thiamine, with a mean TMP to total thiamine ratio of 63%. Mean whole blood TDP (130 nmol/L) and total thiamine in breast-milk (755 nmol/L) were within the upper range reported for well-nourished women. The prevalence of women with low whole blood TDP (<65 nmol/L) was 5% and with deficient breast-milk total thiamine (<300 nmol/L) was 4%. Whole blood TDP predicted both breast-milk thiamine and TMP (R 2 = 0.36 and 0.10, p<0.001). A ratio of TMP to total thiamine ≥63% was associated with a 7.5 and 4-fold higher risk of low whole blood TDP and deficient total breast-milk thiamine, respectively. Routine provision of daily 100 mg of thiamine mononitrate post-partum compared to the previous weekly 10 mg of thiamine hydrochloride resulted in significantly higher total thiamine in breast-milk. Conclusions/Significance Thiamine supplementation for lactating women in Maela refugee camp is effective and should be continued. TMP and its ratio to total thiamine in breast-milk, reported for the first time in this study, provided useful information on thiamine status and should be included in future studies of breast-milk thiamine.

show abstract

Section: Discussionsupporting

confidence: 73%

Thiamine Diphosphate in Whole Blood, Thiamine and Thiamine Monophosphate in Breast-Milk in a Refugee Population

et al. 2012

View full text Add to dashboard Cite

show abstract

Gehalte der Vitamine B1, B2, A und E sowie β-Carotin in transitorischer Frauenmilch und Vergleichsuntersuchungen im Blut der Mütter und im Nabelschnurblut

et al. 1997

View full text Add to dashboard Cite

The contents of the vitamins B1 (27 ng/ml), B2 (57 ng/ml), A (1.3 micrograms/ml), and E (9.7 micrograms/ml) as well as beta-carotene (0.2 microgram/ml) in transitional human milk were determined for up to 35 women aged between 19 and 31 years. Additionally, the vitamin content in maternal and cord plasma as well as the erythrocytic transketolase- and glutathione-reductase activities of the water soluble vitamins were measured. Dietary recalls were evaluated for the nutritional intake of vitamins. Concerning the fat soluble vitamins, the breast fed newborns received the recommended amounts of the German Society of Nutrition (DGE) for this group. In contrast to this, the supply of the water soluble vitamins (B1: 13.5 micrograms/500 ml; B2: 28.5 micrograms/500 ml) attained only 5 to 10% of the recommendations for newborns during the first two weeks after parturition with breast feeding. Vitamin content of maternal plasma (B1: 6.1 +/- 2.8 ng/ml) and erythrocytic enzyme activities (alpha ETK: 0.86-1.62; alpha EGR: 1.08-1.75) indicated a low or sufficient intake, while the values in cord blood (B1: 19.8 +/- 6.5 ng/ml; alpha ETK: 0.62-1.62; alpha EGR: 1.01-1.47) were in accordance with a satisfactory supply.

show abstract

Thiamin status during the third trimester of pregnancy and its influence on thiamin concentrations in transition and mature breast milk

et al. 2004

View full text Add to dashboard Cite

Thiamin deficiency remains an important public health problem in some populations. The aim of the present investigation was to study thiamin status during the third trimester of pregnancy and its influence on the concentration of this vitamin in transition (days 13 -14 of lactation) and mature breast milk (day 40 of lactation) in a group of Spanish women. The pregnancies and lactation periods of fifty-one healthy women 18 -35 (mean 26·7 (SD 3·7)) years old were monitored. Vitamin intake during the third trimester was determined by recording the consumption of foods over 5 d and of the quantities provided by dietary supplements. Thiamin status during this stage of pregnancy was determined by measuring the activation coefficient of erythrocyte transketolase (a-ETK). Milk thiamin content was estimated (in 41% of the subjects) by oxidizing thiamin to thiocrome and measuring fluorescence. Subjects with thiamin intakes above that recommended (group H) had more satisfactory serum a-ETK coefficients (1·01 (SD 0·19)) than did those with lower intakes (group L) (1·21 (SD 0·30); P,0·05). Mature milk thiamin concentrations were significantly higher in group H subjects (0·59 (SD 0·44) mmol/l) than group L subjects (0·25 (SD 0·07) mmol/l). Subjects with a-ETK coefficients . 1·25 in the third trimester had significantly lower mature milk thiamin concentration (0·31 (SD 0·10) mmol/l) than did subjects with more satisfactory a-ETK levels at this time (0·55 (SD 0·42) mmol/l; P, 0·05). The thiamin status of women can be improved since 25·5% of subjects took less than that recommended and 13·7% showed signs of severe deficiency (a-ETK .1·25). The influence of maternal thiamin intake on a-ETK coefficients and on mature breast milk thiamin concentration is confirmed.

show abstract

Mineral and vitamin content of mature breast milk of Saudi lactating mothers

Cited by 6 publications

References 35 publications

Thiamine Diphosphate in Whole Blood, Thiamine and Thiamine Monophosphate in Breast-Milk in a Refugee Population

Thiamine Diphosphate in Whole Blood, Thiamine and Thiamine Monophosphate in Breast-Milk in a Refugee Population

Gehalte der Vitamine B1, B2, A und E sowie β-Carotin in transitorischer Frauenmilch und Vergleichsuntersuchungen im Blut der Mütter und im Nabelschnurblut

Thiamin status during the third trimester of pregnancy and its influence on thiamin concentrations in transition and mature breast milk

Contact Info

Product

Resources

About