In the past decades, several iron ore occurrences have been discovered in the Precambrian Belt of southern Cameroon, with focus on their economic potential, and little attention on the deposit type. However, few studies have been geared towards understanding the different deposit types within this region. This paper seeks to provide new insight on the different styles of iron ore mineralisation of two potential, yet least studied iron ore deposits in this region in addition to enhancing exploration efforts within the different prospects. Petrology and geochemistry of rock samples from the Binga and Djadom iron prospects in southern Cameroon are investigated. The structural disposition of the prospects was mapped and cores described, sampled and subsequently analysed to enhance the understanding of the alteration mineralogy, ore mineralogy and textural features of the iron-bearing lithologies. Polished thin sections were studied by standard microscopy while the bulk rock geochemistry was determined by X-ray fluorescence (XRF) for major and trace elements. At Binga, the main rock types are magnetite gneisses, amphibolites, quartz-biotite gneisses, and mafic intrusions, while the main rocks encountered at Djadom are magnetite gneisses, amphibolitic BIFs, quartz-biotite gneisses, amphibolites and fault rocks. At both prospects, the target lithology for iron ore is the magnetite gneiss. The magnetite gneisses at the Binga prospect are weakly to moderately foliated, but strongly foliated at Djadom, and both contain fractures that are healed by irregular magnetite.