Miniature scar-carcinoma of the lung and the “upper sulcus tumour” of Pancoast

A Study of the Origin and Development of Lung Cancer

“…The growth found in Case 8 and shown in Fig. 7 is very similar to that in the two cases described by James and Pagel (1944), and the description of their cases leaves little doubt that their two cases were but further examples of malignant change supervening in lung scar tissue at the apices of lungs.…”

“…Except for a few reported cases of small, peripherally situated tumours (Gray and Cordonnier, 1929;Stewart and Allison, 1943;James and Pagel, 1944;Petersen, Hunter, and Sneeden, 1949;Spain and Parsonnet, 1951;Prior and Jones, 1952) arnd one describing two minute growths in main bronchi (Aufses and Neuhof, 1952), very little attempt has been made to trace the origin of this very common tumour by looking for the earliest stages in its development. Because the larger bronchi are so frequently involved in the later spread of the disease it is usually assumed that most growths started in the main bronchi.…”

Surgery in the Treatment of Locally Advanced Lung Carcinoma

“…6) showing a normal appearance in spite of the complete block in the prosthesis. muscles, may exceptionally be caused by a malignant tumour not of pulmonary origin, which, at the time of its description (Pancoast, 1924 ;1932), was known as the Pancoast tumour. Pancoast (1932) called this specific tumour a superior pulmonary sulcus tumour 'because this term implies its approximate location and a lack of origin from the lung, pleura, ribs, and mediastinum'.…”

“…Pancoast tumours, distinct from lung carcinoma, have been described by Clarke (1934), by Morris and Harken (1940), and by Herbut and Watson (1946), who consider they arise in bronchial rests, and by Fried (1948), who designates the lesion a sternoclavicular branchioma. James and Pagel (1944), though considering the tumour a specific entity, suggested that miniature scar carcinoma of the lung with involvement of the thoracic inlet is more descriptive of the pathology. This definition leaves unanswered the important question whether the adjacent lung should or should not be resected with the tumour.…”

Malignant Change in Bronchiectasis

“…In the lung, instances have been recorded where cancer has been found, apparently originating in the walls of tuberculous cavities, in the " fibrous apical cap" (James and Pagel, 1944) and, according to several authors including Schwartz (1950), in bronchial scars resulting from tuberculous ulceration.…”