Miopatía del enfermo crítico. Valoración neurofisiológica y biopsia muscular en 33 pacientes

Fernandez-Lorente, J.; Esteban, Angel; Salinero, Emilio Chuvieco; Traba, A.; Prieto, Julio; Palencia, Eduardo

doi:10.33588/rn.5012.2009477

Cited by 4 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nevertheless, other diagnosis could be considered in the two cases of severe CIP, as a coexisting myopathy or an axonal GBS (that sometimes had elevated CK levels) 29 because of the absence of MUAP activation and NCS responses. The percentage of CIM is similar to other group findingsdin 33 ICU patients, 79% had neurophysiological criteria of myopathic disorder, confirmed with muscular biopsy, 10 and in 53 critically ill patients, CIM was diagnosed in 68% and CIP in 38%. 30 Acute focal neuropathies were also frequent in our group, reported in 54.6% patients.…”

Section: Discussionsupporting

confidence: 88%

“…Serum CK and muscular or nerve biopsy may also be useful. 6,9,10 Only few cases of acute neuromuscular disease possibly related to COVID-19 infection have been describeddsome cases of Guillain-Barré syndrome (GBS) 7,[11][12][13][14][15][16][17][18] and some patients diagnosed of CIM. [19][20][21] However, to our knowledge, a study describing the neurophysiological findings in a group of ICU hospitalized COVID-19 patients has not been previously reported.…”

Section: Discussionmentioning

confidence: 99%

“…6,22 In CIM, CMAP amplitudes are normal or reduced and prolonged CMAP duration seems a specific feature. 9,10,23 Sensory nerve action potentials amplitudes are preserved but may be decreased by some factors as limb edema. Critical illness polyneuromyopathy is diagnosed in case CIP, and CIM features coexist.…”

Section: Diagnostic Neurophysiological Criteriamentioning

confidence: 99%

See 2 more Smart Citations

Neurophysiological Findings in Critical COVID-19 Patients With Peripheral Nervous System Manifestations

Santiago-Pérez

Espinosa-Garcia

Martínez-Pérez

et al. 2021

Journal of Clinical Neurophysiology

View full text Add to dashboard Cite

Introduction:Coronavirus disease 2019 patients hospitalized in intensive care units develop neuromuscular manifestations. However, to our knowledge, a study describing the neurophysiological findings in these patients has not been reported. The objective of this study was to diagnose the cause of neuromuscular deficit in severe coronavirus disease 2019 patients, through neurophysiological examination.Methods:This is a retrospective, observational case series. Data were collected from April 13, 2020, to May 31, 2020. Twenty-two coronavirus disease 2019 patients with generalized neuromuscular deficit during intensive care unit hospitalization were studied. Neurophysiological examinations included motor and sensory peripheral nerve conductions, needle electromyography, F waves, and repetitive nerve stimulation.Results:The subjects were 14 men (63.6%) and eight women, ranged from 35 to 74 years old (58.0, interquartile ranges 50.7–66.2). Intensive care unit hospitalization time ranged from 14 to 82 days (median 37.5, interquartile ranges 22.7–55.0). Through neurophysiological examination, myopathy was diagnosed in 17 patients (77.3%) and polyneuropathy in four (18.2%). Focal neuropathies were diagnosed in 12 patients (54.6%), with a total of 19 affected nerves. Common peroneal nerve lesions at the fibular head (68.4%) and ulnar nerve lesions at the elbow level (21.1%) were the most frequent locations. No significant differences were established between neurophysiological findings and clinical or analytical data.Conclusions:In critical coronavirus disease 2019 patients with neuromuscular complaints, neurophysiological examination provides an accurate diagnosis—useful to select treatment measures and establish the prognosis of recovery. Neurophysiological findings are similar to those described for critical illness neuromuscular disease, with myopathy being the most frequent diagnosis.

show abstract

Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Neurophysiological Findings in Critical COVID-19 Patients With Peripheral Nervous System Manifestations

Santiago-Pérez

Espinosa-Garcia

Martínez-Pérez

et al. 2021

Journal of Clinical Neurophysiology

View full text Add to dashboard Cite

show abstract

Perioperative Management of Patients with Neuromuscular Disorders

Bertorini¹,

Bassam

et al. 2011

Neuromuscular Disorders: Treatment and Management

View full text Add to dashboard Cite

Stepwise Approach to Myopathy in Systemic Disease

Chawla¹

2011

Front. Neur.

View full text Add to dashboard Cite

Muscle diseases can constitute a large variety of both acquired and hereditary disorders. Myopathies in systemic disease results from several different disease processes including endocrine, inflammatory, paraneoplastic, infectious, drug- and toxin-induced, critical illness myopathy, metabolic, and myopathies with other systemic disorders. Patients with systemic myopathies often present acutely or sub acutely. On the other hand, familial myopathies or dystrophies generally present in a chronic fashion with exceptions of metabolic myopathies where symptoms on occasion can be precipitated acutely. Most of the inflammatory myopathies can have a chance association with malignant lesions; the incidence appears to be specifically increased only in patients with dermatomyositis. In dealing with myopathies associated with systemic illnesses, the focus will be on the acquired causes. Management is beyond the scope of this chapter. Prognosis is based upon the underlying cause and, most of the time, carries a good prognosis. In order to approach a patient with suspected myopathy from systemic disease, a stepwise approach is utilized.

show abstract

Miopatía del enfermo crítico. Valoración neurofisiológica y biopsia muscular en 33 pacientes

Cited by 4 publications

References 0 publications

Neurophysiological Findings in Critical COVID-19 Patients With Peripheral Nervous System Manifestations

Neurophysiological Findings in Critical COVID-19 Patients With Peripheral Nervous System Manifestations

Perioperative Management of Patients with Neuromuscular Disorders

Stepwise Approach to Myopathy in Systemic Disease

Contact Info

Product

Resources

About