Inherited neuropathies are among the most prevalent inherited neurologic disorders, and with current advances in molecular biology and genetic testing, the clinical spectrum of phenotype/genotype has been expanding enormously. Genetic testing is nowadays commercially available to several subtypes although many remain because of unknown genetic defect. A stepwise rational approach, which is shown in , facilitates reaching a specific diagnosis and reduces the cost.

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The causes of low back pain range from ruptured lumbar disks and spinal stenosis to compression fractures and osteoarthritis. Although surgery may be indicated in some cases, conservative measures are often effective, and preventive regimens may be successful in patients who are obese or otherwise physically unfit. In patients who have been injured on the job or in an automobile accident, the question of compensation may hinder treatment. Hysterical patients may need psychiatric referral.