Mirror-Image Arachnoid Cysts in a Pair of Monozygotic Twins: A Case Report and Review of the Literature

Zhou, Jingyi; Pu, Jiali; Chen, Sheng; Yuan, Hong; Ling, Chenhan; Zhang, Jianmin

doi:10.7150/ijms.8.402

Cited by 12 publications

(11 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…40 Since arachnoid cysts are common, these reports of patients with cysts in association with any of these syndromes do nothing to prove anything more than a coincidental association. The strongest evidence for an association with arachnoid cysts has been provided by a case control study on autosomal dominant polycystic kidney disease and arachnoid cysts by Schievink et al 77 Finally, case reports of twins 36,107 or siblings 102 with arachnoid cysts must also be viewed with skepticism in the context of what is now known about cyst prevalence.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and natural history of arachnoid cysts in adults

Al-Holou¹,

Terman²,

Kilburg³

et al. 2013

JNS

289

230

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Prevalence and natural history of arachnoid cysts in adults

Al-Holou¹,

Terman²,

Kilburg³

et al. 2013

JNS

289

230

View full text Add to dashboard Cite

show abstract

“…Microtia occurring in mirror-image twins has also been reported [18]. Pathologic mirror-imaging has been reported in intracranial conditions like arachnoid cysts [19,20].…”

Section: Discussionmentioning

confidence: 89%

“…In monozygotic twins, there is always a risk of conjoined twins, such as ischiophagus [20]. This mechanism involves fission more likely than fusion [21].…”

Section: Discussionmentioning

confidence: 99%

Mirror-Image Identical Twins Presenting in Mirror-Image Hip Cysts: A Case Report and Review of the Literature

Song¹,

Song²,

Shim³

et al. 2013

Rheumatol Curr Res

View full text Add to dashboard Cite

One-third of twins are monozygotic. Of monozygotic twins, 25% of them are mirror images. Mirror-imaging occurs when pathologic conditions are present on opposite sides of the body. This is the first case report of mirror-image identical twins with opposite hip pain that were found to have small cysts of the femoral head on opposite hips.Case presentation: 38 year-old mirror-image Asian female identical twins presented with hip pain on opposite sides. MRI demonstrated a 4 mm cyst of the anterior aspect of the left hip, the femoral head and neck junction, with a herniation pit on opposite sides. The right-handed twin had the cyst on the right hip, and the left-handed twin had the cyst on the left hip. Conclusion:Mirror-image pathology in mirror-image monozygotic twins suggests possible cytogenetic factors involved in the etiology of various medical problems. If an identical twin presents with a medical problem, it may be recommended to perform a medical diagnostic work-up on the other twin.

show abstract

“…These observations suggest a possible genetic component in the development of some arachnoid cysts. Mirror image arachnoid cysts in a pair of monozygotic twins also support the genetic origin, and these cysts are also known to occur in cases of Aicardi and Panayiotopoulos syndromes [5,6] Some cysts may rupture spontaneously resulting in life threatening hemorrhagic complications. [7][8][9] The proportion of imaged arachnoid cysts that ruptured or hemorrhaged was 6%.…”

mentioning

confidence: 88%

Intracranial arachnoid cysts

Reddy

2013

Neurol India

View full text Add to dashboard Cite

Arachnoid cysts are benign mass lesions of congenital origin containing cerebrospinal fluid (CSF) like material and are enclosed inside a membrane resembling arachnoid. These common lesions are mostly found incidentally because of increased use of neuroimaging. Precise etiology of these lesions and their natural history remain poorly defined and, hence, their optimal treatment guidelines have not yet been established. Majorities of the cases are asymptomatic and are compatible with normal life while some cases grow, and few even resolve spontaneously. Surgery is required in symptomatic cases with expanding cysts, some with bleeds and others with an evolving hydrocephalus of obstructive nature. The results of various surgical interventions in 68 adult patients with intracranial arachnoid cysts have been reviewed in this issue of the journal. [1] Arachnoid cysts arise during development by splitting or duplication of the arachnoid membrane and account for 1% of all intracranial mass lesions. Different hypotheses have been postulated to explain the development of arachnoid cysts such as agenesis of brain structures, arachnoiditis, active fluid secretion, and pulsatile pump nature of fluid collection. Slit valve mechanism observed by cine-mode magnetic resonance imaging (MRI) preoperatively and confirmed during the endoscopic intervention has been reported for the fluid collection in the cysts. [2] Larger cysts can cause hydrocephalus by mass effect by blocking the aqueduct and in some, there could be intra-ventricular abnormalities such as membrane obstructing the aqueduct, occlusion of the foramen of Munro, and obstruction of aqueduct by quadrigeminal cyst, etc., These intra-ventricular anomalies and the cysts may have a common origin. Arachnoid cysts are a frequent finding on intracranial imaging in children. In one study of 11,738 consecutive series of MRI in children over an 11-year period, the prevalence rate of arachnoid cysts was 2.6%. [3] After a mean follow-up of 3.5 years, out of 111 patients, 11 increased in size, 13 decreased in size, and 87 remained stable. A younger age at presentation was significantly associated with cyst enlargement and no patient older than 4 years of age at the time of initial diagnosis had cyst enlargement nor demonstrated new symptoms. In another study in adults, 48,417 patients underwent MRI over a 12-year period and arachnoid cysts were identified in 661 patients with a prevalence of 1.4%. [4] Thirty-five of these cysts were symptomatic and 24 of them needed surgery. There is strong predilection for intracranial arachnoid cysts in the temporal fossa, followed by frontal convexity, posterior fossa, suprasellar region, quadrigeminal area, and lastly, in the ventricles. Rarely, the cysts could be located in brain parenchyma itself. More cysts are located on the left side and in men, whereas, cerebellopontine cysts are found frequently in women and on the right side. These observations suggest a possible genetic component in the development of some arachnoid cysts. Mirror image ar...

show abstract

Mirror-Image Arachnoid Cysts in a Pair of Monozygotic Twins: A Case Report and Review of the Literature

Cited by 12 publications

References 19 publications

Prevalence and natural history of arachnoid cysts in adults

Prevalence and natural history of arachnoid cysts in adults

Mirror-Image Identical Twins Presenting in Mirror-Image Hip Cysts: A Case Report and Review of the Literature

Intracranial arachnoid cysts

Contact Info

Product

Resources

About