Mitigating dispersive spectrometer size-performance limitations with HTVS optical components

Meade, Jeffery T.; Behr, Bradford B.; Bismilla, Yusuf; Cenko, Andrew T.; DesRoches, Brandon; Henkin, Arie; Munro, Elizabeth A.; Slaa, Jared; Baker, Scott; Rempel, David; Hajian, Arsen R.

doi:10.1117/12.2039945

Cited by 1 publication

(1 citation statement)

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“…Some modern spectrometers are now available with entrance optics that asymmetrically image the source onto a virtual slit at the focal plane of the spectrometer so utilising the full available height of the entrance aperture and hence the maximum possible étendue of the spectrometer. 86 Whatever configuration is used the étendue is still conserved and the overall system efficiency is always governed by the least efficient component.…”

Section: Maximising Throughputmentioning

confidence: 99%

Developing fibre optic Raman probes for applications in clinical spectroscopy

et al. 2016

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Raman spectroscopy has been shown by various groups over the last two decades to have significant capability in discriminating disease states in bodily fluids, cells and tissues. Recent development in instrumentation, optics and manufacturing approaches has facilitated the design and demonstration of various novel in vivo probes, which have applicability for myriad of applications. This review focusses on key considerations and recommendations for application specific clinical Raman probe design and construction. Raman probes can be utilised as clinical tools able to provide rapid, non-invasive, real-time molecular analysis of disease specific changes in tissues. Clearly the target tissue location, the significiance of spectral changes with disease and the possible access routes to the region of interest will vary for each clinical application considered. This review provides insight into design and construction considerations, including suitable probe designs and manufacturing materials compatible with Raman spectroscopy.

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Section: Maximising Throughputmentioning

confidence: 99%