“…Although better feasibility of MV repair has been demonstrated in patients with healed IE than in those with active IE, surgery during the active phase of IE should frequently be selected to prevent additional thromboembolic events, minimize ongoing valvular destruction, and achieve earlier relief of acute volume overload to the left ventricle (LV) caused by mitral regurgitation (MR). 1,2 The combination of autologous pericardial patch repair, artificial chordal replacement, and annuloplasty has enabled complex MV repair, but suture stress on inflamed valve tissues may result in recurrence of MR. 1 If the feasibility of MV repair appears uncertain, based on preoperative echocardiography, it should not be recommended as an elective operation, but may be preferred in patients with active IE and high-risk comorbidities, such as neurological, hematological, or immunological complications. This study reviewed the results of surgery in patients in the active phase of native mitral valve IE.…”