Mixed Ligand Complexes Derived from Isoniazid and Amino Acid: Preparation, Characterization and Anti-tuberculosis Assay

Abstract

A range of mixed ligand complexes derived from the reaction of alanine (alan), glycine (gly)and isoniazid (ison) ligands with Cr ) and Ni +2 , w = 0, n = 3, Y = 2Cl).The analyses data indicated distorted octahedral geometries about metal centres. The bio-assay of the prepared complexes show a positive activity against normal tuberculosis bacteria. However, the complexes exhibit no activity against the resistance tuberculosis bacteria.

Synthesis and Characterization Zn(II)LeucinDithiocarbamate Complex and Their Potential as Anti-Tuberculosis

“…The (C=N) amine stretching band at 1583,56 cm -1 for the complexes compound. That band is assigned to a (C=N) and can be attributed to delocalization of metal electron transition to the π → π* system of the ligand 11 . The ν(C-S) is written as v(C S) cm -1 stretching frequency appeared in the wave number range 950-1050 cm -1 16 .…”

Studies on Some Mixed Ligand Ternary Complexes of Cerium(III) Employing 1-Nitroso-2-naphthol and Amino Acids

“…The literature survey revealed that mixed ligand complexes of some transition metals with amino acids have been studied for their synthesis, spectral and biological importance [1], like antibacterial [2][3][4], antimicrobial [5,6], antituberculosis assay [7] and as a potential therapeutic agents [8]. The mixed ligand complexes of 1-nitroso-2-naphthol with transition and inner transitiom metals have been reported [9][10][11].…”