Mixed Mammary Carcinosarcoma in Domesticated Asian Palm Civet (Paradoxurus hermaphroditus).

Prakoso, YA; Widyawati, Ratna; Wirjaatmadja, Roeswandono; Kurnianto, Ady; Kurniasih, Kurniasih

doi:10.36380/scil.2019.wvj7

Cited by 3 publications

(3 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Furthermore, osseous metaplasia with glomeruloid bodies has been observed in several specimens. Osseous metaplasia is the common metaplastic transformation within a soft tissue such as the endometrial tissue ( Prakoso et al , 2019 ), however, the presentation of osseous metaplasia within the kidney is a rare and unique case. The other findings are the fibrous histiocytoma-like cells and emperipolesis.…”

Section: Discussionmentioning

confidence: 99%

Clinicopathological study of sarcomatoid renal cell carcinoma in animals in East Java, Indonesia, from 2017 to 2022

Prakoso¹,

Widyarini²,

Faresy³

et al. 2023

Open Vet J

View full text Add to dashboard Cite

Background: Renal cell carcinoma (RCC) is common cancer derived from the renal epithelium. One of the rarest cases of RCC is sarcomatoid RCC (sRCC). The occurrence of sRCC in animals is not clearly demonstrated. Aim: This study aimed to observe the clinicopathological characteristics of sRCC in animals from East Java, Indonesia, from 2017 to 2022. Methods: This study used patients which were histopathologically diagnosed with sRCC in our laboratory from 2017 to 2022. The data of clinical characteristics of animals, hematology, serology, histopathology, and immunohistochemistry were retrieved and tabulated. The data was qualitatively and quantitatively analyzed using a simple descriptive method and SPSS version 26, respectively. Results: Fourteen cases of sRCC in animals have been identified in this study. It was found in rodents, dogs, and cats. sRCC predominantly occurred in rodents (57.14%) without specific clinical signs. The common histopathological findings of sRCC were epithelial renal cells transition into elongated atypical spindle cells. In addition, other histopathological patterns of a renal epithelial cell such as clear cell, tubule-cystic, and papillary also have been found. Immunohistochemistry by using antibodies demonstrates that PAX8 is expressed on sRCC tissue samples 92.85% (13/14 samples). Hence, PAX8 could be used as a supporting method for establishing the diagnosis of sRCC in animals. Hematology and serological tests did not correlate to type of sRCC either pure sRCC or dedifferentiated sRCC. sRCC result in hypercreatinemia in rodents and dogs. Conclusions: This study shows that the incidence of sRCC in animals is rare. Animals with sRCC did not show any specific clinical signs. The histopathological finding is quite difficult to be differentiated from the other RCC. PAX8 expression on renal tissue samples is useful in supporting the diagnosis of sRCC in animals.

show abstract

Section: Discussionmentioning

confidence: 99%

Clinicopathological study of sarcomatoid renal cell carcinoma in animals in East Java, Indonesia, from 2017 to 2022

Prakoso¹,

Widyarini²,

Faresy³

et al. 2023

Open Vet J

View full text Add to dashboard Cite

show abstract

“…bertambah banyak sehingga terlihat gambaran kasar dan berkelompok di tepi inti (hiperkromasi), inti sel juga ditemukan memiliki beberapa inti (Arimbi et al, 2013). Adenokarsinoma kelenjar mammae juga ditandai dengan adanya diferensiasi satu atau kedua sel mesenkim dan epitel (Prakoso et al, 2019).…”

Section: Pembahasanunclassified

Adenokarsinoma pada Kelenjar Ambing Kucing Ras Himalaya: Tampilan Klinik, Penanganan dengan Mastektomi dan Hasilnya

Pemayun,

Rahmatullah,

Batan

2023

jveteriner

View full text Add to dashboard Cite

Adenokarsinoma kelenjar mammae adalah pertumbuhan sel-sel kelenjar yang tidak terkontrol dan tidak terkoordinasi umumnya dijumpai pada anjing dan jarang pada kucing. Adenokarsinoma mammae pada kucing bersifat malignant dan merusak jaringan kelenjar mammae secara progresif, sehingga berakibat fatal pada kucing. Seekor kucing Himalaya berusia 4 tahun, berjenis kelamin betina yang belum disteril, bobot badan 3 kg, warna bulu coklat tua, mengalami pembengkakan pada satu kelenjar mammae bagian belakang sebelah kanan dan tidak mau mengecil. Pemeriksaan dengan palpasi adanya massa yang menonjol cukup besar, terasa keras dan padat pada kelenjar mammae. Hasil pemeriksaan histopatologi jaringan tumor, kucing didiagnosa menderita adenokarsinoma ditandai dengan sel-sel kelenjar mengalami proliferasi tidak terkontrol, bersifat infiltratif, adanya proses angiogenesis, adanya sel-sel tumor pada pembuluh darah kelenjar, ductus, bentuk dan ukuran ductus yang bervariasi (pleomorfik). Penanganan dilakukan dengan pembedahan mastektomi yaitu pengangkatan kelenjar mammae yang terdapat jaringan tumor. Pascaoperasi kucing diberikan cefotaxime 20 mg/kg BB IV (q12h), dan tolfedine 4 mg/kg BB IM (q24h) selama tiga hari dan dilanjutkan dengan pemberian cefixime trihydrate 10 mg/kg BB (q12h), dan deksametason 0,08 mg/ kg BB (q12h) secara oral selama 5 hari. Kucing dinyatakan sembuh pada hari ke 14 pascaoperasi dengan luka operasi telah mengering, nafsu makan, minum baik, defikasi dan urinasi normal serta pemeriksaan radiografi, dan hematologi kucing dalam keadaan normal.

show abstract

“…Teknik mastektomi unilateral yang dilakukan pada pasien sebagai antisipasi terhadap adanya metastasis tumor yang berkelanjutan (Papazoglou et al, 2014). Selain itu, pemilihan teknik ini untuk penanganan tumor kelejar mammae ganda, yaitu tumor muncul di lebih dari satu kelenjar mammae, terdapat lesi berukuran >3 cm pada kelenjar kranial abdomen dan ketika nodul tersebar di sepanjang rantai kelenjar mammae serta untuk membuat satu luka bedah tunggal (Prakoso et al, 2019;Horta et al, 2015). Pertimbangan lainnya bahwa penanganan bedah tumor mammae harus didasarkan pada faktor drainase limfatik, jumlah dan ukuran lesi, dan faktor prognostik yang ditetapkan pada masingmasing kasus (Horta et al, 2015).…”

Section: Hasil Dan Pembahasanunclassified

Surgical Procedure for Pyometra and Mammae Tumor Treatment in a Pitbull Dog

Rickyawan

Virgiantari²,

Lesmana³

et al. 2022

J. Med. Vet.

View full text Add to dashboard Cite

Pyometra is an infection or inflammation of the uterine wall characterized by the accumulation of pus in the uterine lumen. Predisposing factors include age, breed, bacterial infection, and hormones. Another disease that is often correlated with an imbalance in reproductive hormones is mammary tumors. A 7-year-old unspayed female Pitbull dog weighed 27.9 kg has clinical symptoms of frequent discharge of mucopurulent reddish-brown discharge with a foul odor from the vagina. The left mammary glands of the second, third, and fourth nipples have lumps about 20 cm in diameter, are solid in consistency, well-defined, the same color as the skin surface, and can be moved. Diagnosis performed on physical examination, hematology, blood chemistry, and cytology was pyometra and mammary tumors. Treatment was done by ovariohysterectomy and unilateral mastectomy. Post-surgery therapy was enrofloxacin 5 mg/kg, ketoprofen 2 mg/kg, phytomenadione 1 mg/kg, and Biodin® 0.1 ml/kg, followed by intensive surgical wound care. The patient recovered after two months of treatment.

show abstract

Mixed Mammary Carcinosarcoma in Domesticated Asian Palm Civet (Paradoxurus hermaphroditus).

Cited by 3 publications

References 21 publications

Clinicopathological study of sarcomatoid renal cell carcinoma in animals in East Java, Indonesia, from 2017 to 2022

Clinicopathological study of sarcomatoid renal cell carcinoma in animals in East Java, Indonesia, from 2017 to 2022

Adenokarsinoma pada Kelenjar Ambing Kucing Ras Himalaya: Tampilan Klinik, Penanganan dengan Mastektomi dan Hasilnya

Surgical Procedure for Pyometra and Mammae Tumor Treatment in a Pitbull Dog

Contact Info

Product

Resources

About