Mixed micelle formation between amino acid-based surfactants and phospholipids

Effect of sodium chloride on interaction between amino sulfonate amphoteric surfactant and octylphenol polyoxyethylene ether (10) in aqueous solution

“…The values of b12 obtained from this fit are À3.394 AE 0.082 according to the Rodenas's model and À3.361 AE 0.076 according to the Motomura's model, respectively. For all mixed systems, the activity coefficients in mixed micelles (f 1 and f 2 ) were calculated from Eq.…”

“…Among these mixed systems, the observed synergism can be referred to as nonideal mixing, whereas the antagonism properties can be attributed to the repulsion between their molecules. Based on the regular solution theory (RST), the Rubingh model [3] introduces an important parameter, the interaction parameter (b 12 ), which helps us to predict the attraction or repulsion between the two surfactants. For a nonideal mixed system, another parameter, activity coefficient (f), was also introduced into some models [3,4] and was used to partly describe the difference between the nonideal and ideal mixing of surfactants.…”

“…A larger number of investigations [4][5][6][7][8][9][10][11][12] have been reported the interacting behaviors for the mixed surfactant systems in aqueous solutions in the absence of inorganic salts. Nevertheless, in many engineering applications, the inorganic salts always exist In aqueous solution containing the NaCl of 0.25 mol/L, the micellization of binary mixtures of sodium dodecyl diamino sulfonate (C12AS) and octylphenol polyoxyethylene ether (10) (OP-10) have been investigated employing both the UV-vis spectroscopy method, using pyrene as a probe, and the tensiometric method.…”

Solubilization power of an amino acid-based gemini surfactant towards the hydrophobic drug amphotericin B

“…The gemini surfactant (C 8 Cys) 2 was synthesized according to established literature procedures [36][37][38][39][40] and fully characterized as described elsewhere [36,37]. Amphotericin B from Streptomyces sp.…”

“…1) and studied its supramolecular behaviour in aqueous media both in the absence and in the presence of biological (macro)molecules [36][37][38][39][40]. In the present work (C 8 Cys) 2 is characterized and evaluated as a potential delivery agent for AmB and compared A c c e p t e d M a n u s c r i p t 3 with NaDC used in the commercial formulation Fungizone.…”