Significant improvement in the respiratory care management inRussian Federationduring the previous five years has resulted in improvement in diagnosis of respiratory diseases, quality of outpatient and in-hospital care, and decrease in mortality from respiratory diseases. This is a review of scientific papers, books, and guidelines published by researchers of the Federal Pulmonology Research Institute. The review reflects a contribution of the institute staff to the improvement of respiratory care and the public health inRussia. The main scientific directions of the institute are the public health monitoring and epidemiological studies that evaluate prevalence of respiratory diseases inRussia. Other research directions include improvement in the primary and secondary prevention, improvement in primary and specialized outpatient and in-hospital respiratory care management, and improvement in diagnosis and treatment of work-related respiratory diseases. Novel approaches to respiratory care of advanced disease, post-surgery rehabilitation and orphan respiratory diseases have been described in the article. To improve prevention of the diseases, novel markers of chronic respiratory diseases were searched and new medications were evaluated. The authors concluded that further scientific directions of Russian pulmonology could include molecular investigations of respiratory diseases, prevention and early diagnosis of orphan diseases, personalized management and rehabilitation of patients with chronic respiratory diseases and implementation of innovative methods of diagnosis, treatment and rehabilitation aimed at further decrease in mortality from respiratory diseases.