Mobile Genetic Elements and Quantitative Characters in Drosophila: Fast Heritable Changes Under Temperature Treatment

Ratner, V. A.; Vasilyeva, L. A.

doi:10.1007/978-3-642-74525-6_11

Cited by 8 publications

(10 citation statements)

References 16 publications

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“…There have also been theories about the evolutionary importance of the genome system of MGE genomic patterns after environmental stress (temperature, etc.) (4,5,(10)(11)(12).…”

Section: Introductionmentioning

confidence: 99%

“…There have also been theories about the evolutionary importance of the genome system of MGE genomic patterns after environmental stress (temperature, etc.) (4,5,(10)(11)(12).However, the data are incomplete. Vasilyeva and coworkers (1-3, 13) in most of their work used heterogeneous Drosophila lines, and in situ hybridization was done many tens of generations after temperature treatment.…”

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confidence: 99%

“…Vasilyeva and coworkers (1)(2)(3)(4)(5) discovered the effects of stepwise temperature treatment of Drosophila at specially sensitive periods of the pupal stage. The heritable changes of expression of the mutant radius incompletus (ri) were seen accompanied by the changed patterns of localization of copia-like MGEs.…”

mentioning

confidence: 99%

“…From this evidence, speculations and hypotheses have been advanced about the genetic system of HS regulation in relation to heritable temperature effects in Drosophila (4,5,(10)(11)(12). There have also been theories about the evolutionary importance of the genome system of MGE genomic patterns after environmental stress (temperature, etc.)…”

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confidence: 99%

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Induction of the mobile genetic element Dm-412 transpositions in the Drosophila genome by heat shock treatment.

Ratner¹,

Zabanov²,

Kolesnikova³

et al. 1992

Proc. Natl. Acad. Sci. U.S.A.

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Males of a Drosophila melanogaster isogenic line with a mutation of the major gene for radius incompletus (ri) were treated by standard light heat shock (3TC for 90 min) and by heavy heat shock (transfer of males from 37C for 2 hr to 4rC for 1 hr and back; this procedure was repeated three times). In the F1 generation of treated males mated with nontreated females of the same isogenic line, mass transpositions of copia-like mobile genetic element Dm-412 were found. The altered positions ofthe element seem nonrandom; five "hot spots" of transposition were found. Probabilities of transpositions were estimated after light heat shock and heavy heat shock and in the control sample. These probabilities were, respectively, 3.4 x 10-2, 8.7 x 10-2, and <4.1 x 10-4 transpositions per genome per occupied position per generation. Therefore, as a result of heat shock treatment, the probabilities of transpositions were two orders of magnitude greater than those of the control sample in the next generation after induction. Comparison of the results with those after stepwise temperature treatment shows that the induction depends on the intensity of the stress action (temperature treatment) rather than on the type of the stress action. (7) and HS regulation sites (8, 9). After HS treatment of flies, transcription and transposition of different MGEs seemed to be activated (9-11).From this evidence, speculations and hypotheses have been advanced about the genetic system of HS regulation in relation to heritable temperature effects in Drosophila (4, 5, 10-12). There have also been theories about the evolutionary importance of the genome system of MGE genomic patterns after environmental stress (temperature, etc.) (4,5,(10)(11)(12).However, the data are incomplete. Vasilyeva and coworkers (1-3, 13) in most of their work used heterogeneous Drosophila lines, and in situ hybridization was done many tens of generations after temperature treatment. Indeed, in some repeated experiments this interval was decreased to several generations with the same results. But the possibility of selective influence was not excluded completely. Junakovic et al. (6) found the effects in the next generation, but their restriction fragments were not compared with patterns of MGE localization in polytene chromosomes.In this paper (see also ref. 14), we present data that demonstrate multiple transpositions of copia-like MGE Dm-412 in the next generation after HS treatment. This work was done with an isogenic Drosophila line to decrease pattern variability in the control sample and after treatment. MATERIALS AND METHODSIsogenic Lines. The isogenic lines with a mutation of the major gene for ri were created by using marked balanced chromosomes (15): M5 (X chromosome), Cy/Pm (chromosome 2), D/Sb (chromosome 3). Of 20 isogenic lines, one (N 49) was used for the HS treatment, being most stable in its pattern of MGE Dm412 localization and expression of the character ri.Control Sample. Young males and virgin females were collected from mass cultures of isog...

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“…There have also been theories about the evolutionary importance of the genome system of MGE genomic patterns after environmental stress (temperature, etc.) (4,5,(10)(11)(12).…”

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Induction of the mobile genetic element Dm-412 transpositions in the Drosophila genome by heat shock treatment.

Ratner¹,

Zabanov²,

Kolesnikova³

et al. 1992

Proc. Natl. Acad. Sci. U.S.A.

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“…Anxolabéhère et al, 1989) and more questionable in its real evolutionary significance is the observation that in some populations of Drosophila jtemperature shock produces the widespread or even the generalized appearance of certain modifications in wings venation, and that, under certain conditions (particular developmental stages) such changes are inherited as they are due to what one could call a mass migration of certain trasposons from their usual location to other «preordained» locations (cp. Ratner & Vasilyeva, 1990). When we try to envisage the relevance of these observations for evolution, it seems that such events, which vindicate some old claims by Waddington (1953), may, in fact, as it is indicated by some field observations, speed up changes in frequency of certain genetic variants, but it is hard to see how, under natural conditions they may cause a sudden stable generalized change in a whole population, except, perhaps, as quite exceptional events, the sort of exception which confirms the rule, and that will be very, very difficult to verify in the field.…”

Section: Hennigian or Transformed Cladistic Species And Biologymentioning

confidence: 99%

Problems of systematics: Part 1. A critical evaluation of the ≪species problem≫ and its significance in evolutionary biology

Simonetta¹

1992

Bolletino di zoologia

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FOREWORDThe present paper belongs to a planned short series aiming to contribute to the clarification of some basic problems of evolutionary biology and systematics, but also to stress the need for all zoologists to be well aware of such problems and of their relevance to all aspects of our trade (Simonetta, 1990 and in preparation). On one hand, indeed, ecologists and population geneticists are fully aware of the need for their researches to be based on good systematic foundations and of the dearth of reliable systematists. However they are not so conscious, perhaps, of the fact that there is a real danger that recruitment of new systematists may promote a sort of honest practitioner who uncritically rely on disputable general theories and methods with dire results for their classifications. On the other hand many laboratory biologists tend to ignore current theoretical debates and shut themselves up in the ivory tower of their own specialities, unaware of how shaky its foundations are when not understood in a broader framework. INTRODUCTION ABSTRACTThe author discusses the significance of the «species problem» in the context of evolutionary biology and of systematics. He concludes that, contrary to current tendencies, a strongly nominalistic concept of the «species» is the only tenable one, that species cannot be conceived as individuals and that the species concept is irrelevant for evolutionary biology. Moreover a careful analysis of the species concept falsifies some of the basic tenets of Hennigian and of transformed cladism.

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Addendum

Ratner¹,

Zharkikh²,

Колчанов³

et al. 1996

Molecular Evolution

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Mobile Genetic Elements and Quantitative Characters in Drosophila: Fast Heritable Changes Under Temperature Treatment

Cited by 8 publications

References 16 publications

Induction of the mobile genetic element Dm-412 transpositions in the Drosophila genome by heat shock treatment.

Induction of the mobile genetic element Dm-412 transpositions in the Drosophila genome by heat shock treatment.

Problems of systematics: Part 1. A critical evaluation of the ≪species problem≫ and its significance in evolutionary biology

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