Mobile health interventions for improving colorectal cancer screening rates: A systematic review and meta-analysis

Abstract

Objective: The aim of this systematic review and meta-analysis was to determine the efficacy of different mHealth interventions in increasing colorectal cancer (CRC) screening rates. Methods: A literature search for eligible studies was done in ClinicalTrials.gov, PubMed, and Scopus in October 2020. Included studies were randomized controlled trials done on adults due for CRC screening, who received either an mHealth intervention to promote screening or usual care. The primary outcome from these studies was completion of CRC screening. Two reviewers independently worked on selecting studies, collecting data, and determining risk of bias. Adjusted odds ratios (AOR) for CRC screening rates were summarized into a Forest plot. Results: A total of ten trials from three continents were included in the qualitative analysis. Risk of bias is low in terms of randomization, but high in terms of participant blinding, due to the nature of the interventions. Meta-analysis of four trials showed low clinical and statistical heterogeneity (I 2 =0%). Overall, the use of mHealth interventions is associated with higher CRC screening uptake when compared to usual care (AOR 1.33; 95% CI, 1.20-1.46). This effect was seen across different types of mHealth interventions, which included automated and non-automated telephone education and text-message reminders. Conclusion: This study showed that mHealth is associated with increased CRC screening participation regardless of the type of intervention used.

Digital health and telehealth in cancer care: a scoping review of reviews

“…The remaining 134 reviews met eligibility criteria and were included in the synthesis. 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 …”

Design and evaluation of a colon cancer mobile application

“…The results of the study indicated the positive effect of the software in identifying suspicious symptoms of colorectal cancer on the participants’ self-evaluation and willingness to participate in screening programs ( P < 0.05). Elepaño, et al also, in a systematic review, found that mHealth interventions, such as telephone intervention and text messages, were associated with a 20–46% increase in colorectal cancer screening rates compared to usual care [ 20 ]. The results of the current research have shown evidence similar to theirs.…”

Performance of different colorectal cancer screening strategies: a long-term passive follow-up population-based screening program in Beijing, China

“…Nowadays, with the advancement of communication technology, people prefer to read from their mobile phone using mobile applications or web browsers rather than the traditional printed material. Previous studies have demonstrated that mobile phone-based health education could improve residents' knowledge of CRC prevention [37][38][39]. In addition, mobile phone-based text message reminders could also increase the participation rate of CRC screening among the target population [40][41].…”