The technological development of the last decades have been able to push human to develop their needs, so a way to new demands were opened and this can lead to a complexity problem. Thereby, a good interoperability between the product design activities can lead to the possibility of ensuring a promising satisfaction to all requirements. However, the major problem is the enormous discontinuity between them. Indeed, each one treats the product from its point of view without recourse to the requirements defined by others. This paper is interested in the collaborative work that brings together the system engineer, who deals with the system from a global view, and the designer, who is a specialist in the detailed design, in order to validate requirements. A new methodology has been proposed to define the role of each one in the design process. This methodology focuses on the product development cycle from the analysis of needs to the validation phase. This obviously requires interoperability between the two domains of Model Based System Engineering (MBSE) and Computer Aided Design (CAD). Based on a pedal bicycle case study which is an industrial mechatronic product, the proposed methodology will be illustrated for validation and highlighting its advantages and limitations.