Industry era 4.0 poses challenges for Small and Medium Enterprises (SMEs) to expand their business into the global market, but there are still many obstacles related to resources and technology readiness. This study aims to analyze the influence of business strategy quality, seller behavior ethics, process innovation, entrepreneurship orientation perspective, and business environment adaptability toward SMEs' business performance. This study uses a quantitative approach to investigate the mediation role of competitive advantage. The sample that used in this study is 80 SMEs' batik center entrepreneurs in Central Java, which taken uses purposive sampling method. The data are analyzed using Partial Least Square Structural Equation Modeling (PLS-SEM) with SmartPLS software. The results show that business strategy quality and seller behavioral ethics partially positive effect on competitive advantage. The second finding shows the business strategy quality, seller behavior ethic, process innovation, entrepreneurship orientation perspective, business environment adaptability, and partial competitive advantage positively affect business performance. This study expected contributes to the theoretical development, especially for strategic management.