The polymer injection is part of the tertiary methods used to enhance the oil recovery when the conventional water flooding is not efficient. The addition of polymer in low concentration can delay the breakthrough of the injected phase and improve the sweep and displacement efficiencies. The use of a biopolymer is an environmentally friendly alternative to take advantage of the properties of the polymeric solutions using biodegradable additives.On the other hand, the combination of chemical EOR methods with nanotechnology has received lots of attention due to the advantages of the nanoparticles in the reductions of the interfacial tension and contact angle, which can contribute to residual oil mobilization.This experimental study evaluates a workflow to design a biopolymer fluid for enhanced oil recovery (EOR) processes, from fluid characterization to core flooding tests, using water-wet porous media. Three criteria were applied to evaluate the biopolymers used in this study. In the first part, the fluids were tested in terms of fluid-fluid and fluid-solid performance.In the second part (microfluidic approach), the fluids were evaluated in three scenarios, combining the inclusion of different polymer and silica nanoparticles in the solution to be injected. In the last step of the methodology, the solution with the best performance was evaluated in a core flooding test.The fluids characterization showed that biopolymer's content did not affect the ability of the nanoparticles to reduce the interfacial tension and make the surface more waterwet. Additionally, the biopolymers reduced the aggregation of nanoparticles in the solution.Also, the viscosity of the solutions was not affected by the interaction of the biopolymers with the silica nanoparticles. The micromodel test performed with the nanoparticles-assisted Xanthan showed the smallest oil clusters and the highest ultimate oil recovery compared to the Xanthan Gum, Scleroglucan, brine, and nanofluid floodings. Finally, a core flooding test was run to evaluate Xanthan Gum flooding on oil recovery. As a result, the oil production was slightly anticipated, but water breakthrough delay was not evident. At the end of both processes, the polymeric solution increases the ultimate oil recovery factor by 9.4% when compared to conventional water injection.