The microgrids design for remote locations represents one of the most important and critical applications of the microgrid concept. It requires the correct sizing and the proper utilization of the different sources to guarantee the economical feasibility and the reliability of the supply. This study illustrates an efficiency-based power management strategy, designed for an undergoing microgrid project, where the sizing process of the resources (diesel generators, battery energy storage system, and PV plant) is obtained using a mixed-integer optimization algorithm. The proposed power management strategy guarantees the efficient exploitation of the power sources, which is one of the key elements of the optimal sizing process, being naturally included in the definition of the energy cost functions. The effectiveness of the power control strategy is validated by means of quasi-dynamic simulations on the complete microgrid model, where sources are defined by the optimal problem solution, while the cabling (size and length) and the main switchboards location reflect the expected system layout. Results obtained from the simulation of the microgrid electrical system include losses, and allow to verify and to highlight the desired quantities, such as the quality of supply at each busbar (voltage magnitude), and the state of charge of the energy storage system.