2000
DOI: 10.1002/(sici)1097-0290(20000105)67:1<19::aid-bit3>3.0.co;2-c
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Modeling of biological processes using self-cycling fermentation and genetic algorithms

Abstract: Self-cycling fermentation (SCF) was coupled with a genetic algorithm (GA) to provide a simple system for evaluating biological models. The SCF provided the necessary system excitation and data "richness" required to completely define the fitted biological models. The solution scheme based on the GA avoided the computational difficulties often associated with calculusbased nonlinear regression techniques, resulting in rapid and accurate convergence. After validating the mathematical approach, data from the SCF … Show more

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Cited by 12 publications
(2 citation statements)
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“…Introducing eqn (21) into eqn (20), we obtain the entropic density of any trajectory f {x[u(t)],u(t),t}:…”
Section: Measuring the Sensitivitymentioning
confidence: 99%
See 1 more Smart Citation
“…Introducing eqn (21) into eqn (20), we obtain the entropic density of any trajectory f {x[u(t)],u(t),t}:…”
Section: Measuring the Sensitivitymentioning
confidence: 99%
“…A piecewise approximation of the optimal control trajectory was sought, either constant or linear over a time interval, and the GA technique was applied to find it. GA is a method extensively used especially in the last two decades, taking advantage of the progress in computational capacities [13,2123].…”
Section: Introductionmentioning
confidence: 99%