This test-bed was developed to investigate the tribological behavior of the thrust bearings -the key parts of submersible pumps, in the simulating work conditions in oil well. A great deal of Electromagnetic Interferences (EMI) are unavoidable and will lead to system failure or abnormal data in condition of quite high load and speed. On the basis of analysis and investigation of interference source and mode in system, such as power interference, vector control inverter, mechanical contact, static interference and so on, propose several hardware case, such as new power EMI filter, electromagnetic shielding, RC link, impedance matching, etc., were employed, and novel digital filtering algorithm, in measurement and control system of test-bed. The results showed that the combination of the different anti-interference methods can reach optimal reliability and precision.