Modeling of industrial crystallizers for control and design purposes

Kramer, Herman J. M.; Dijkstra, Jelke; Verheijen, P.J.T.; Rosmalen, G.M. van

doi:10.1016/s0032-5910(99)00219-3

Cited by 27 publications

(20 citation statements)

References 3 publications

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“…To this problem has to be added the limited validity of existing models in terms of an extrapolation to other scales of operations or other geometries. This is due to the fact that available models still are input-output models which are tuned for a single configuration [18]. In real processes, fluid dynamics and crystallization are closely interrelated and should be modeled together [19].…”

Section: Design Of Fluid Dynamics For Each Equipment and Each Productmentioning

confidence: 99%

“…Thus, to obtain a rigorous process description an anisotropic flow field in the crystallizer needs to be considered, and consequently, also the population balance problem has to be simultaneously solved with the fluid dynamics Equations [20]. Various approaches to solve the corresponding simulation problem and to demonstrate the importance of the interaction of fluid dynamics and crystallization are discussed in the literature [18,17,21]. However, these problems are far from being solved.…”

Section: Design Of Fluid Dynamics For Each Equipment and Each Productmentioning

confidence: 99%

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Problems, potentials and future of industrial crystallization

Ulrich

Frohberg

2013

Front. Chem. Sci. Eng.

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This review discusses important research developments and arising challenges in the field of industrial crystallization with an emphasis on recent problems. The most relevant areas of research have been identified. These are the prediction of phase diagrams; the prediction of effects of impurities and additives; the design of fluid dynamics; the process control with process analytical technologies (PAT) tools; the polymorph and solvate screening; the stabilization of non-stable phases; and the product design. The potential of industrial crystallization in various areas is outlined and discussed with particular reference to the product quality, process design, and control. On this basis, possible future directions for research and development have been pointed out to highlight the importance of crystallization as an outstanding technique for separation, purification as well as for product design.

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Section: Design Of Fluid Dynamics For Each Equipment and Each Productmentioning

confidence: 99%

Section: Design Of Fluid Dynamics For Each Equipment and Each Productmentioning

confidence: 99%

Problems, potentials and future of industrial crystallization

Ulrich

Frohberg

2013

Front. Chem. Sci. Eng.

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“…The heating medium to the heat exchanger enters and leaves at (12) and (13), respectively. Figure 2B) [5] The slurry leaving the crystallizer (at 8) is divided into two parts.…”

Section: Apv Kestner Evaporative Crystallizermentioning

confidence: 99%

CFD simulation and comparison of industrial crystallizers

et al. 2014

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Simulation of flow patterns in eleven industrial crystallizers (standard Messo, Cerny direct contact, Swenson draft tube baffled, Swenson walker, Swenson evaporative, Oslo cooling, Oslo Krystal, APV Kestner, Batch Vacuum, stirred tank with disc turbine, and stirred tank with pitched blade impeller) have been carried out using computational fluid dynamics (CFD). Population balance modelling (PBM) is coupled with CFD to obtain better results. In all the cases, the crystallizer volume was 100 liter and the power consumption per unit volume was 1 kW/m 3 . The simulation results have been presented in terms of mean velocity components, turbulent kinetic energy and dissipation rate. On the basis of the flow patterns, these eleven crystallizers have been compared for crystal size distribution (CSD). It was found that Swenson Evaporative, Krystal and Batch Vacuum provide relatively low CSD.

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“…Set of such ideallymixed compartments represents different regions of the crystallizer. This approach has been well described in the literature (Kramer et al, 2000). It is difficult to claim the superiority of one of these approaches over the other.…”

Section: Crystallization In Tubementioning

confidence: 99%

Simulation of CaCO3 Crystal Growth in Multiphase Reaction

Gierycz¹

2012

Modern Aspects of Bulk Crystal and Thin Film Preparation

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Modeling of industrial crystallizers for control and design purposes

Cited by 27 publications

References 3 publications

Problems, potentials and future of industrial crystallization

Problems, potentials and future of industrial crystallization

CFD simulation and comparison of industrial crystallizers

Simulation of CaCO3 Crystal Growth in Multiphase Reaction

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