“…DC (3.33, 6.66, 9.99, 13.33 and 16.66%), ultrasonication time (3, 5, 7, 9 and 11 min), cavitation intensity (75.41, 150.82, 226.24, 301.65, 377.07 W/cm 2 ) and amplitude of sonication (30,40,50, 60, 70%) were standardized serially one after the other in this order by using previously reported standard values for synthesis of such formulations for optimization of the preceding parameters [10] . In each case, the minimum statistically significant particle size was the criterion for selection of the best value.…”